Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
Embryonic development of the Mediterranean starfish Hacelia attenuata
Abstract Background Starfish play essential ecological roles as predators and ecosystem regulators; however, detailed developmental descriptions exist for only a handful of species, none of which are from the Mediterranean Sea. Results In this study, we provide the first full account of the development of the Mediterranean starfish Hacelia attenuata ...
Silvia Caballero‐Mancebo +3 more
wiley +1 more source
Green reaction media enable chemodivergent oxidation of vanillyl alcohol, selectively affording vanillin or its fully oxidized counterpart, vanillic acid. The use of an earth‐abundant, inexpensive, and nontoxic iron catalyst for the transformation of lignin‐derived alcohol to fine chemicals underscores the sustainability of the process. A low E‐factor (
Rasmiranjan Hota +2 more
wiley +1 more source
Sphincter-Preserving Therapy with Topical 2% Diltiazem for Chronic Anal Fissure: Our Experience [PDF]
Background: Chronic anal fissure is a common problem across the world treated largely by surgical methods. Studies have demonstrated the efficacy of topical agents like Glyceryl Trinitrate (GTN) in anal fissure but it has been shown to have side ...
Manish Swarnkar +3 more
doaj
Botulinum toxin A in the treatment of anal fissure [PDF]
Background. This paper presents our first experience in the treatment of primary anal fissure by injection of botulinum A toxin into the internal sphincter. Methods.
Stanković Nebojša, Mirković Darko
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Vinylene‐linked DPP polymers with expanded thiophene donors achieve strengthened interchain π‐π stacking in near‐amorphous films, enabling high charge mobility and outstanding mechanical stability for flexible organic thin‐film transistors. Abstract Flexible organic thin‐film transistors (OTFTs) based on multi‐vinylene‐linked diketopyrrolopyrrole (DPP)
Yanlin Chen +11 more
wiley +1 more source
Anal Fissure: Is it becoming a medical disorder? Review Article
An anal fissure which does not heal with conservative measures as sits baths and laxatives is a chronic anal fissure. Physiologically, it is the high resting tone of the internal anal sphincter that chiefly interferes with the healing process of these ...
Ali Al-shaham, +2 more
doaj
Recent Advances in the Pharmacotherapy of Chronic Anal Fissure: An Update
Surgical sphincterotomy reduces anal tone and sphincter spasm and promotes ulcer healing. Because the surgery is associated with the side effect of faecal incontinence, pharmacological agents to treat chronic anal fissure have been explored recently ...
Bikash Medhi +5 more
doaj +1 more source
Advances in Immunological Combination Therapy for Colorectal Cancer
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu +7 more
wiley +1 more source
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
wiley +1 more source

