Results 81 to 90 of about 5,821 (197)
Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances
MedComm, Volume 7, Issue 9, September 2026.Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait +5 more
wiley +1 more source
Role of Lateral Internal Sphincterotomy in the Surgical Treatment of Chronic Anal Fissure
Gomal Journal of Medical Sciences, 2010 Background: Lateral internal sphincterotomy is one of the many treatment modalities for chronic anal fissure. This study was designed to evaluate the outcome of lateral internal sphincterotomy for the treatment of chronic anal fissure.
Muhammad Tayyab +2 more
doaj
Protein Science, Volume 35, Issue 9, September 2026.Abstract Disulfide‐rich miniproteins constitute compact and highly stable scaffolds of growing interest for molecular and structural engineering. Schistosomins are ~80‐residue proteins conserved across gastropods that form a long‐standing orphan family whose structure and biological roles have remained unknown.
Oleg Melnyk +13 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 64, Issue 5, Page 603-614, September 2026.StaySure is a novel anal insert device that safely and effectively treats medically refractory faecal incontinence. Treatment reduced incontinence episodes by 69%, improved quality of life beyond clinically meaningful thresholds, and was well tolerated with no treatment‐related serious adverse events. ABSTRACT Background Treatment options for medically‐
Adil E. Bharucha +6 more
wiley +1 more source
A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
Advanced Science, Volume 13, Issue 43, 3 August 2026.A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2020 Objective: To compare the efficacy of topical 0.2% glyceryl trinitrate (GTN) ointment with 2% Nifedipine ointment in healing of anal fissure. Study Design: Quasi experimental study.
Usman Asghar +4 more
doaj +2 more sources
Semi‐Artificial Breeding Report of Endangered Chitala lopis Using Hormonal Induction Treatments
Aquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.The graphical abstract of the first successful semi‐artificial breeding of the endangered Giant Featherback (Chitala lopis, Bleeker 1851) by hormonal induction ABSTRACT Reproductive maturity of Chitala lopis is critical for preventing species loss, as the species was previously listed as critically endangered on the IUCN Red List.
Boby Muslimin +18 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1821-1831, August 2026.ABSTRACT There is a strong genetic contribution to the etiology of congenital diaphragmatic hernia (CDH). This study evaluated genetic testing results and diagnostic yield for fetuses and children with CDH. This was a retrospective cohort study of exome sequencing (ES) performed at GeneDx for fetuses and children ≤ 18 years of age with CDH compared ...
Justin Blair +9 more
wiley +1 more source
Topical Sucralfate for Treatment of Chronic Anal Fissure. [PDF]
J Anus Rectum Colon, 2023 Lohsiriwat V, Mongkhonsupphawan A.
europepmc +1 more source
Archiv der Pharmazie, Volume 359, Issue 8, August 2026.A series of 25 functionalized indeno[1,2‐b]indoles was selected from in‐house compound library and additional synthesis work. Capillary electrophoresis‐based and thermal shift assays, X‐ray analysis of small molecules, and co‐crystallization studies highlighted a key molecular template for the inhibitory potential of protein kinase CK2.
Matheus M. Guimarães +18 more
wiley +1 more source