Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
The Journal of Physiology, EarlyView.Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
Neuraxial analgesia in pregnant individuals with bleeding disorders: a retrospective descriptive study of obstetric anesthesia practices and outcomes. [PDF]
Res Pract Thromb HaemostYi Y +6 more
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend We developed a novel ovine model of diet‐induced maternal obesity, where ewes were fed a control or obesogenic diet for 60 days pre‐pregnancy and throughout gestation. Pregnant ewes were surgically instrumented to assess maternal cardiovascular function near term.
Rachael C. Crew +8 more
wiley +1 more source
"Scientific trends of pharmacological methods in labor pain management: bibliometric analysis of epidural, spinal, and other approaches, 2000-2025". [PDF]
Rev Assoc Med Bras (1992)Gültepe R.
europepmc +1 more source
Clinical predictors of postpartum vaginal and vulvar hematomas and the need for surgical treatment
Pregnancy, Volume 2, Issue 4, July 2026.Abstract Objective To identify risk factors for postpartum vaginal or vulvar hematoma and to determine clinical predictors of surgical intervention. Study design A retrospective matched case‐control study was conducted at a tertiary, university‐affiliated center (2012–2024).
Itai Atar +5 more
wiley +1 more source
Physiotherapist-led ultrasound-guided visual biofeedback prelabor training: a randomised controlled trial. [PDF]
BMC Pregnancy ChildbirthBen-Ami N +6 more
europepmc +1 more source
Society for Maternal‐Fetal Medicine Statement: Acetaminophen use during pregnancy
Pregnancy, Volume 2, Issue 4, July 2026.Abstract Acetaminophen has long been considered safe to use during pregnancy. A growing body of cohort studies and meta‐analyses has explored the potential association between prenatal acetaminophen use and neurodevelopmental outcomes in children. Although some studies report modestly increased risks of neurodevelopmental disorders in children exposed ...
Society for Maternal‐Fetal Medicine (SMFM) +1 more
wiley +1 more source
Do no harm: Surgeons should be leaders in opioid stewardship. [PDF]
Can J SurgAntonsen AN, Wiseman SM.
europepmc +1 more source
Changes in cardiotochography following combined spinal-epidural labor analgesia [PDF]
, 2009 ABRÃO, Karen Cristine +2 more
core +2 more sources
In utero ventriculosubgaleal shunt placement in a fetal lamb model: Phase 1 technical insights
Pregnancy, Volume 2, Issue 4, July 2026.Abstract Background Progressive ventriculomegaly and the resulting irreversible brain damage may be mitigated through timely diversion prenatal intervention. While ventriculosubgaleal shunt (VSGS) is commonly performed postnatally in premature infants, in utero placement is unexplored.
Shohra Qaderi +24 more
wiley +1 more source