Results 171 to 180 of about 88,297 (307)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, Volume 20, Issue 9, Page 2203-2219, September 2026.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Neuraxial Homeostasis – Optimizing Neuraxial Labor Analgesia

open access: yes
Jianwei Guo, Yan Cheng, Minmin Yi Department of Anesthesiology, Shaanxi Provincial People’s Hospital, Xi’an, Shaanxi, 710068, People’s Republic of ChinaCorrespondence: Yan Cheng, Department of Anesthesiology, Shaanxi Provincial People’s Hospital, Xi’an ...
Guo J, Yi M, Cheng Y
core  

Charting Morphotoxicity With Complementary Embryo Models

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx   +9 more
wiley   +1 more source

Physiotherapist-led ultrasound-guided visual biofeedback prelabor training: a randomised controlled trial. [PDF]

open access: yesBMC Pregnancy Childbirth
Ben-Ami N   +6 more
europepmc   +1 more source

Codeine toxicity via breast Milk: Can this occur and implications for opiate therapy in children

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3012-3016, September 2026.
Codeine is commonly used in combination analgesic products. The use of codeine during breastfeeding can rarely be associated with serious adverse effects related to genetic polymorphisms affecting codeine's metabolism and disposition. Clinicians treating infants of breastfeeding mothers should be aware of this rare but potentially serious complication.
Michael Rieder
wiley   +1 more source

Giant Primary Ovarian Leiomyoma Mimicking Ovarian Malignancy in an Elderly Postmenopausal Woman: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Ovarian leiomyomas, either primary or parasitic in origin, are exceptionally rare and account for about 0.5% to 1% of all benign ovarian tumors. They often pose a diagnostic challenge, particularly in postmenopausal women, as they can clinically and radiologically mimic ovarian malignancy.
John Lugata   +8 more
wiley   +1 more source

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