Results 181 to 190 of about 8,694 (298)

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair

British Journal of Pharmacology, Volume 183, Issue 11, Page 2947-2968, June 2026.
Background and Purpose Endometriosis is a chronic, hormone‐dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, its impact on lesion regression is limited, possibly due to apoptosis resistance and ...
Yujie Peng, Meng Zhang, Libo Zhu, Wenqiang Qian, Jingjing Yan, Huidi Jiang, Yu Xin, Ying Zhang, Dongli Sun, Weidong Fei, Mengdan Zhao   +10 more
wiley   +1 more source

The Impact of Maternal BMI on the Efficacy and Safety of Oral Misoprostol for Labor Induction. [PDF]

Pharmaceuticals (Basel)
Socha MW, Flis W, Sowińska J, Stankiewicz M, Kazdepka-Ziemińska A.   +4 more
europepmc   +1 more source

Hierarchical Channeled Graphitized Nanoarchitecture as a Diagnostic Platform for Maternal Fever Warning

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin, Ning Li, Heyuhan Zhang, Xufang Hu, Zhiqiang Liu, Chunhui Deng   +5 more
wiley   +1 more source

Comparative efficacy of hyperbaric bupivacaine <i>vs</i> hyperbaric ropivacaine in spinal anesthesia for cesarean section: A meta-analysis. [PDF]

World J Methodol
Anand R, Nag DS, Patel R, Sharma P, Uppalapati VK, Singh UK.   +5 more
europepmc   +1 more source

Low‐intervention clinical trials in Spain: Do they progress?

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1438-1444, May 2026.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza, Mayro J. Cortés Pestana, Kristopher Amaro, Rosa M. Antonijoan, Caridad Pontes   +4 more
wiley   +1 more source

Treatment of breakthrough labor pain with epidural dexmedetomidine: a case series. [PDF]

Proc (Bayl Univ Med Cent)
Blanton A, Tombul Z, Beck R, Tao W, Mootz AA.   +4 more
europepmc   +1 more source

Through Parents' Eyes: Reframing Neonatal Pain Assessment Through Lived Experience

Paediatric and Neonatal Pain, Volume 8, Issue 2, June 2026.
Linda Ng, Rob Eley, Priya Govindaswamy, Emre Ilhan, Ahmed Moustafa   +4 more
wiley   +1 more source

A Large Pedunculated Subserosal Leiomyoma Masquerading as a Pelvic Tumor in Early Pregnancy: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Uterine leiomyomas, commonly known as fibroids, are the most prevalent pelvic tumors in females, affecting 20%–30% of women of reproductive age. However, large pedunculated subserosal leiomyomas presenting during early pregnancy are uncommon and may mimic adnexal or intra‐abdominal malignancies, posing diagnostic and management challenges ...
John Lugata, Felix Luginga, Tecla Lyamuya, Glory Maringo, Eusebious Maro, Alex Mremi, Bariki Mchome   +6 more
wiley   +1 more source

Cough-induced rectus sheath hematoma during pregnancy-a rare presentation of abdominal pain. [PDF]

BMC Pregnancy Childbirth
Chen J, Teng X, Wang L, Shen J.
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source