Development of a Pregnancy‐Specific Physiologically Based Pharmacokinetics (PBPK) Model for Aspirin
ABSTRACT Aspirin is one of the most commonly used medications in pregnancy, particularly for the prevention of hypertensive disorders. Despite aspirin's widespread use in pregnancy for preeclampsia prevention, its pharmacokinetics (PK) across all trimesters remain poorly characterized, complicating optimal dosing recommendations. To develop a pregnancy‐
Ana Collins‐Smith +5 more
wiley +1 more source
Cough-induced rectus sheath hematoma during pregnancy-a rare presentation of abdominal pain. [PDF]
Chen J, Teng X, Wang L, Shen J.
europepmc +1 more source
ABSTRACT Background Admission cardiotocography (CTG) remains widely used to assess the fetal condition at the onset of labour in low‐risk pregnancies, despite international guidelines recommending against its routine use and advocating intermittent auscultation (IA) instead.
Mariana Tome +4 more
wiley +1 more source
Repeat spinal anesthesia for intrapartum cesarean section after epidural labor analgesia: a retrospective cohort study of failure rate and the volume-risk relationship. [PDF]
Wei Y, Liu K, Lu X, Wang J, Li J, Yao L.
europepmc +1 more source
Day‐Case Laparoscopic Hysterectomy: A Successful Pilot in Regional New Zealand
ABSTRACT We conducted a day‐case total laparoscopic hysterectomy service improvement project at Nelson Public Hospital, New Zealand, in August and September, 2024. A retrospective analysis was performed, and a voluntary patient questionnaire administered, at the 4‐week postoperative review.
Ben McLaughlin +2 more
wiley +1 more source
Comparative efficacy of hyperbaric bupivacaine <i>vs</i> hyperbaric ropivacaine in spinal anesthesia for cesarean section: A meta-analysis. [PDF]
Anand R +5 more
europepmc +1 more source
Obstetric and early neonatal outcomes and intrapartum fetal blood sampling among 40 309 singleton women undergoing trial of labor by 5‐year periods from 2002 to 2021 at Kuopio University Hospital. Among women undergoing a trial of labor, the use of fetal blood sampling (FBS) steadily declined from 11.7% to 3.7%.
Saana Pietilä +3 more
wiley +1 more source
Addition of Lidocaine to Ropivacaine and Sufentanil for Epidural Labour Analgesia: A Randomised Double-Blind Study on the Incidence of Epidural-Related Maternal Fever. [PDF]
Shen Y +5 more
europepmc +1 more source
ABSTRACT Aim Although evidence supporting mother‐newborn couplet care continues to grow, its clinical integration remains inconsistent due to ongoing barriers. This study aimed to describe current practices of mother‐newborn couplet care in Danish obstetric and neonatal departments.
Joan Neergaard Larsen +6 more
wiley +1 more source

