Results 141 to 150 of about 410,347 (354)

Preemptive analgesia, preventive analgesia and protective analgesia

open access: yesRevista Dor, 2017
Irimar de Paula Posso   +2 more
openaire   +1 more source

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

open access: yesAdvanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan   +9 more
wiley   +1 more source

Anaesthetic Management Including Low-Dose Dexmedetomidine and Butorphanol in Dogs Undergoing ECG-Gated Cardiac Computed Tomography: A Retrospective Case Series

open access: yesVeterinary Sciences
This retrospective case series aims to assess the effects of an anaesthetic protocol including low-dose dexmedetomidine and butorphanol in dogs referred for cardiac tamponade undergoing ECG-gated CCT with contrast medium administration.
Camilla Schiesari   +5 more
doaj   +1 more source

A comparison of high volume/low concentration and low volume/high concentration ropivacaine in caudal analgesia for pediatric orchiopexy

open access: yes, 2009
BACKGROUND: It is unclear whether the volume or concentration of local anesthetic influences its spread and quality of caudal analgesia when the total drug dose is fixed.
한상원   +3 more
core   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

open access: yesAdvanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang   +5 more
wiley   +1 more source

Preventive analgesia for postoperative pain control: a broader concept

open access: yes, 2014
Nalini Vadivelu,1 Sukanya Mitra,2 Erika Schermer,3 Vijay Kodumudi,4 Alan David Kaye,5 Richard D Urman61Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA; 2Department of Anesthesia and Intensive Care, Government Medical ...
Kaye AD   +5 more
core  

Different regimens of epidural analgesia: high dose vs low dose

open access: yes, 2023
reservedBackground: Durante il travaglio di parto, ed il parto stesso, la donna vive un’esperienza dolorifica particolare, multifattoriale ed estremamente variabile.
CONTE, FRANCESCA
core  

Diagnosing the system: Mental health, necropolitical uncare, and the abolition of migration detention

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract This article examines the psychological effects of migration detention in the European Union's Closed Controlled Access Center (CCAC) on Samos through an ecological lens. It explores a double normalization of suffering: the brutalization of necropolitical migration governance and the simultaneous understanding of resulting distress as an ...
Julia Manek
wiley   +1 more source

Clinical Guidelines King Edward Memorial Hospital Perth Western Australia

open access: yes, 2001
Epidural, combined spinal epidural (CSE), labour analgesia, anaesthetist Neuraxial analgesia, using epidural and CSE techniques, is the most effective method of pain relief in labour and is available on request. It is important to discuss with the mother
Labour Analgesia, Key Words
core  

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga   +58 more
wiley   +1 more source

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