Objective Identification of osteoarthritis (OA)–specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi +10 more
wiley +1 more source
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat +14 more
wiley +1 more source
Time to Analgesia Provision for Abdominal Pain Presentations in the Emergency Department: The Effect of Biological Sex-A Retrospective Cohort Study. [PDF]
Walker L +3 more
europepmc +1 more source
Objective To estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axSpA and to identify factors associated with D2M/TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis Program cohort.
Patricia Remalante‐Rayco +8 more
wiley +1 more source
An Investigation of Exercise-Induced Hypoalgesia After Isometric and Cardiovascular Exercise
Exercise-induced hypoalgesia is a well-established phenomenon in the literature. The underlying mechanisms responsible for this augmentation of pain perception are not completely understood.
Drury, Daniel G. +3 more
core
A novel nerve block and anatomy workshop for emergency medicine residents: A pilot study
Abstract Construct a workshop for emergency medicine (EM) residents to learn ultrasound‐guided regional anesthesia (UGRA) procedures and build confidence in performing those procedures. Use pre‐ and post‐workshop knowledge and confidence surveys to determine workshop effectiveness.
Geoffery D. Fernquist +4 more
wiley +1 more source
Randomized controlled trial to compare post operative analgesia between ultrasound guided quadratus lumborum and erector spinae plane block in children undergoing pyeloplasty. [PDF]
Kaur N, Pandey M, Varshney PG, Kundal R.
europepmc +1 more source
Bowtie Technique for Arthroscopic Hip Inversion Labral Repair
Abstract Various suture techniques for arthroscopic hip labral repair have been described to address labral pathology. However, optimal restoration of the labral suction seal relies on proper tension and control of the labral tissue during the repair.
Mathew Park +4 more
wiley +1 more source
Multimodal analgesia strategies enhance postoperative recovery and mitigate inflammatory responses in women undergoing elective surgery for endometrial cancer: a retrospective cohort study. [PDF]
Tang Y, He Y, Yang H, Li H, Mao A.
europepmc +1 more source

