Results 131 to 140 of about 219,594 (315)
Annals of MedicineBackground Clinical observations have shown that brain-derived neurotrophic factor (BDNF) expression is reduced in patients with impaired cognitive function after anaesthesia and surgery. Abnormal epigenetic changes may contribute to this condition.
Tong Wu +6 more
doaj +1 more source
Prenatal Morphine Exposure Decreases Analgesia but Not K+ Channel Activation
, 2009 The present study has investigated the possible supraspinal adaptive changes induced by prenatal administration of morphine, including morphine -induced supraspinal antinociception in vivo, the density and binding affinity ofμ-opioid receptors in the ...
邱麗珠;范書懷;郝政鴻;莊廣傑;陶寶綠 +1 more
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Animal Models and Experimental Medicine, EarlyView.The research strategy for pharmacodynamics, serum pharmacochemistry, metabolomics, and network pharmacology analysis method in intervention effects of LTT are illustrated. Abstract Background Liujing Toutong tablet (LTT) is a traditional Chinese patent medicine.
Zihan Yu +10 more
wiley +1 more source
Development of immunocompetent models for primary and metastatic ER+ breast cancer
Animal Models and Experimental Medicine, EarlyView.This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull +5 more
wiley +1 more source
Journal of Anesthesia, Analgesia and Critical CareBackground Opioid-free anesthesia (OFA) is an innovative approach to anesthesia management aimed at enhancing both the safety and the quality of perioperative outcomes. The efficacy and safety of these approaches are uncertain. The aim of our work was to
Vincenzo Francesco Tripodi +3 more
doaj +1 more source
Preemptive analgesia, preventive analgesia and protective analgesia
Revista Dor, 2017 Irimar de Paula Posso +2 more
openaire +1 more source
Measurement and evaluation of surgical models of spinal fusion in mice, rats, and rabbits
Animal Models and Experimental Medicine, EarlyView.In this study, spinal fusion models in mice, rats and rabbits are compared and discussed. The results show that after comparing the anatomical structure and the complexity of surgical operation, among the three experimental animals in this study, the rabbit as an experimental animal is superior to the mouse and the rat in the establishment of spinal ...
Jianghong Lu, Yicun Hu, Xin Yao
wiley +1 more source
, 1989 Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia produced by morphine injection, footshock, vaginal/cervical stimulation, and during late pregnancy in rats.
Doerr, Jean C., Kristal, Dr. Mark B.
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Animal Models and Experimental Medicine, EarlyView.The graphical abstract shows how molecular biology research has shifted from using traditional animal models toward using methods that are more relevant to humans. It points out the main problems, differences between species, difficulty in reproducing results, moral issues, and lack of infrastructure that make translational accuracy harder to achieve ...
Md. Shajid Hossain Rafi +6 more
wiley +1 more source
Progress in analgesia for labor: focus on neuraxial blocks
, 2009 J Sudharma Ranasinghe, David J BirnbachMiller School of Medicine, University of Miami, Florida, USAAbstract: Neuraxial analgesia is widely accepted as the most effective and the least depressant method of providing pain relief in labor.
Sudharma Ranasinghe, J. +3 more
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