Results 151 to 160 of about 347,788 (376)

Hereditary Multiple Osteochondromas and Acute Lymphoblastic Leukemia: A Possible Role for EXT1 and EXT2 in Hematopoietic Malignancies

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hereditary multiple osteochondromas (HMO) is an autosomal dominant disorder caused by heterozygous deleterious variants in the EXT1 or EXT2 genes. While the clinical core phenotype is well established and mainly consists of bone deformities, limb length discrepancies, multiple benign bone neoplasms, and increased risk of chondrosarcoma, the ...
Francesco Comisi   +7 more
wiley   +1 more source

Copper‐Catalyzed Synthesis of C‐2 Substituted Indolin‐3‐Ones and Indolin‐3‐One [4+2] Cycloadducts Through Azide‐Tethered Iodonium Ylides

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Azide‐tethered iodonium ylides under copper catalysis generate metallocarbenes that undergo intramolecular trapping by the azide moiety and generate a reactive C‐acylimine, effectively coupling two nucleophilic centers. This intermediate can be trapped by a wide range of nucleophiles or 1,3‐dienes producing complex indolin‐3‐ones and ...
Israel Najar Guerrero   +2 more
wiley   +1 more source

Synthesis of Pyrazolidin‐3‐one Derivatives Bearing Trifluoromethyl Group via Cascade Michael/Intramolecular Transamidation Reactions

open access: yesAsian Journal of Organic Chemistry, EarlyView.
The cascade Michael/intramolecular transamidation reactions of 3‐phenacylidene‐2‐indolinone derivatives bearing a trifluoromethyl group as a novel Michael acceptor with hydrazines yielded the corresponding pyrazolidin‐3‐one derivatives in good to high yields with excellent diastereoselectivity.
Ryo Tsuyusaki   +4 more
wiley   +1 more source

Sevoflurane and analgesia [PDF]

open access: yesBritish Journal of Anaesthesia, 2007
S. Grover   +4 more
openaire   +3 more sources

Experimental study of a novel mouse model of tibial shaft fracture combined with blunt chest trauma

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Novel animal models showed the same pathological mechanism and imaging characteristics as those of patients with multiple trauma. Our model is useful for studying whether blocking or interfering with cytokine responses is beneficial in the treatment of multiple trauma patients.
Bing Zhang   +5 more
wiley   +1 more source

Trichlorethylene Analgesia in Labour [PDF]

open access: green, 1951
O. Browne   +2 more
openalex   +1 more source

Analgesia [PDF]

open access: yesPostgraduate Medical Journal, 1955
openaire   +2 more sources

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