Results 241 to 250 of about 328,147 (311)

Dispensing of actionable pharmacogenetic drugs among adults receiving cardiovascular disease medications in the Northern Netherlands: A serial cross‐sectional study

Clinical Pharmacology &Therapeutics, EarlyView.
The extent of pharmacogenetic (PGx) drug dispensing among Dutch adults receiving medications for cardiovascular disease (CVD) is unknown. Using the University of Groningen IADB.nl pharmacy database, we performed a serial cross‐sectional study (2019–2023) to estimate the annual prevalence of PGx drug dispensing and annual rates of initiation.
Zhuolin Zhang, Guiling Zhou, Jens H. J. Bos, Eelko Hak, Talitha Feenstra, Frank Klont   +5 more
wiley   +1 more source

CYP2D6‐Guided Opioid Therapy for Chronic Pain: A Multi‐Center Pragmatic Randomized Controlled Trial

Clinical Pharmacology &Therapeutics, EarlyView.
The analgesic effectiveness of several opioids depends on CYP2D6‐mediated metabolism to more active opioid receptor agonists. CYP2D6 activity is impacted by genetic variability and medications that inhibit CYP2D6. We conducted a pragmatic, multi‐center, randomized, controlled trial to determine whether CYP2D6‐guided opioid prescribing improves chronic ...
Todd C. Skaar, Rachel A. Myers, Roger B. Fillingim, John T. Callaghan, Kerri L. Cavanaugh, Hrishikesh Chakraborty, Jordan F. Baye, Emily J. Cicali, Michael T. Eadon, Erica N. Elwood, Elizabeth C. Harris, Lindsay J. Hines, Khoa A. Nguyen, Michelle A. Ramos, Marc Rosenman, Azita Sadeghpour, Saskia Shuman, Rajbir Singh, Emma M. Tillman, Christina M. Wyatt, Carol R. Horowitz, Deepak Voora, Lori A. Orlando, Josh F. Peterson, Larisa H. Cavallari, Julie A. Johnson, Paul R. Dexter, on behalf of the IGNITE Pragmatic Trials Network, L Orlando, D Voora, C Horowitz, C Horowitz, N Calman, T Skaar, T Skaar, P Dexter, T Skaar, P Dexter, J Johnson, L Cavallari, J Johnson, L Cavallari, J Johnson, L Cavallari, K Blake, K Blake, K Blake, J Peterson, J Peterson, K Cavanaugh, R Singh, R Singh, L Hines, C Wyatt, H Chakraborty, Christina Wyatt, Geoff Ginsburg, Kady‐Ann Steen‐Burrell, Bhargav Adagarla, Sarah George, Beth Harris, Jaclyn Holland, Yashika Johnson, Phyllis Kennel, Kristen Linney, Rania Metry, Rachel Myers, Wanda Parker, Gayle Passmore, Carol Pereira, Teji Rakhra‐Burris, Ryanne Wu, Ruth Lehan, Tyffany Locklear, Carol Horowitz, Michelle Ramos, Sabrina Clermont, Bart Ferket, Kenneth Fifer, Diane Hauser, Joseph Kannry, James Murrough, Aniwaa Owusu Obeng, Janet Seo, Tatiana Sabin, Nandini Shroff, Paul Dexter, Abi Colwell, Amy M. Breman, Zeruesenay Desta, Cathy Fulton, Jennelle C. Hodge, Sheryl Lynch, Jonathan Oliver, Victoria M. Pratt, Ross Robinson, Elizabeth Rowe, Jennifer Stuart, Emma Tillman, Ashley Vetor, Julie Johnson, Larisa Cavallari, Alexander Parker, Erica Elwood, Kathryn Blake, Emily Cicali, Kelsey Cook, Karam Diaby, Julio Duarte, Ben Duong, Karla Giron, Elizabeth Eddy, Julia Krutov, Carol Mathews, Haesuk Park, Robyn Nelson, Ryan Rhoden, Caroline Schlierle, Taylor Sullivan, Almut Winterstein, Kristen Wiisanen, Josh Peterson, Kerri Cavanaugh, Sara Van Driest, Sara Block, Jordan Baye, Michelle Benck, Chantel Bender, Sylvia Eluhu, Colette Free, Shane Gonnelly, Sarah Hedeen, Lindsay Hines, Steve Houtschilt, Michelle Liu, Salisha Marryshow, Nicole Neville, Natasha Petry, Sidd Pratap, Vernon Sherden, Kimberly Snell, Ana Tomescu, Megan Trietsch, James Walker, Deanna Web, Erin Whiting, Russell A. Wilke, Simona Volpi, Sarah Hutchison, Natalie Kucher, Ebony Madden, Jessica Reinach, Renee Rider, Ismail Safi, Ella Samer, Lori Orlando, Lani Banez, Lisa Bendz, Jackie Jordan, Ann McGee, Christina Nix, Lorraine Vergara, Tyler Colon, Aaishah Francis, Samantha Guagliardo, Najiba Khan, Camila Tan Lam, Michelle Sciarrino, Emma Maiman‐Stadtmauer, Sofia Medina‐Pardo, Ololade (Lola) Williams, Sheng Luo, Kevin Anstrom, Alicia Ellis, Stephen Ellis, Hwasoon Kim, Peter Merrill, Lilin She, Jennifer Shepherd, Saira Siddiqui, Jun Wen, Brittany Davis, John Howard, Alia Jamison, Lydia Joyner, Ellie Kiihne, Johnathan Oliver, Libbie Silverman, Jordan Sonneville Jennifer Stuart, Laurel Tokar, Neil Calman, Daviana Buck, Nicole Canchucaja Porshia Cook, Ariel Jacobs Danielle John, Mirta (Mimi) Milanes, Wambui Ngari, Megan Triestch, Abraham Garcia, Carol Gutierrez, Steven Houtschilt, Maria Lopez, Alan Mejia, Anaite Montes Bu, Deanna Webb, Sonja White, Ali Brewer, Brittni Deadrick, Alexis Meyer, Blair Svennes, Hana Al Alshaykh, Tala Basha, Asia Cobb, Brendon Cooper, Amanda Elchynski, Amanda Elsey, Anuksha Gotmare, Lauren Lemke, Arielle Nelson, Michael Read, Genevieve Rosier, Isabella Schultz, Chiara Chermont Spina, Joshua Terrell, Alexa Valko, Precious Williams, Tracy Leonard, David Smith, Marian Davis, Vincent Guerra, Jennifer Salo, Claudia Cartaya Torres, Jorge Valedon, Paola Nieves Viana, Jose Alonso, Jeffery Gainer, Morgan Howard, Fatoumata Kaba, Brianna Rivers, Liliana Serrano, Kimberly Vigal, ADeia Williams, Angelo Lazaro, Salisha Merryshow, Henry Ong, John Thomas Callaghan, Raheleh Rahimi Darabad, Daniel Getu, Katherine Huber, Judive Jocelyn, Robin Morman Li, Rosalena Muckle, Brandi Plunkett, Siegfried Schmidt, Evgenia Teal, Petra Townsend, Joshua R. Wellington   +255 more
wiley   +1 more source

Potential involvement of isolectin B4-positive nociceptors in dorsal root ganglion as an underlying mechanism of the analgesic effect of Tuina in rats. [PDF]

J Tradit Chin Med
Yanbin C, Pengfei S, Guangxin G, Zhiwei WU, Qingguang Z, Min F.   +5 more
europepmc   +1 more source

Medication Use During Breastfeeding—An Understudied Population: A Five‐Year Experience in the Pharmacovigilance Center of Lyon

Clinical Pharmacology &Therapeutics, EarlyView.
Medication use during breastfeeding is common, yet data on drug transfer into breast milk and infant exposure remain limited. This study describes real‐world requests concerning medication compatibility with breastfeeding managed by the Lyon pharmacovigilance center over five years.
Blandine Bertin, Aurore Gouraud, Anthony Facile, Fanny Ledys, Sabrina Pierre, Véronique Pizzoglio, Thierry Vial, Marine Auffret, Marina Atzenhoffer   +8 more
wiley   +1 more source

Effect of adding preoperative serratus anterior plane block to intercostal nerve block with liposomal bupivacaine on postoperative pain in patients undergoing video-assisted thoracoscopic lung resection: study protocol for a prospective randomized controlled trial. [PDF]

Front Med (Lausanne)
Liang H, Cui Q, Wang Q, Ding H, Zhou Y, Ling Z, Ran M, Tang L.   +7 more
europepmc   +1 more source

Mapping the scientific landscape of regional analgesia for total knee arthroplasty: A bibliometric study. [PDF]

Saudi J Anaesth
Nair AS, Al Sawafi S, Sural SM, Al Batrani A, Mistry T.   +4 more
europepmc   +1 more source

The opioid-sparing efficacy of ultrasound-guided quadro-iliac plane block versus transversus abdominis plane block after cesarean delivery: A randomized controlled trial. [PDF]

Saudi J Anaesth
Salama MA, Al Dammas FK, AlDhuwaihy A, Almalki MA, Alhakbani TM, AlAhmari YF, Alarifi R, Alhabeeb J, Nagy M, Shaaban AA, Taraby A.   +10 more
europepmc   +1 more source

PaSo paracetamol with strong opioids trial: paracetamol versus placebo in conjunction with strong opioids for cancer pain-a pilot randomised placebo-controlled withdrawal trial. [PDF]

BMJ Support Palliat Care
Hagen KMR, McWilliams K, Bowden J, Harvie K, Paulsen Ø, Fallon M.   +5 more
europepmc   +1 more source

Associations of <i>OPRM1</i>, <i>COMT</i>, and <i>ABCB1</i> Variants with Opioid Analgesic Response in Acute Renal Colic: A Candidate-Gene Study. [PDF]

Pharmaceuticals (Basel)
Ün S, Sabırlı R, Türkçüer İ, Lengerova G, Bozhkova M, Petrov S, Köseler A.   +6 more
europepmc   +1 more source

Opiranserin (VVZ-149): what's new in analgesics. [PDF]

Korean J Pain
Kim KH.
europepmc   +1 more source