Results 21 to 30 of about 615,257 (306)

Emergency Department Pain Management Following Implementation of a Geriatric Hip Fracture Program [PDF]

open access: yes, 2017
Introduction: Over 300,000 patients in the United States sustain low-trauma fragility hip fractures annually. Multidisciplinary geriatric fracture programs (GFP) including early, multimodal pain management reduce morbidity and mortality. Our overall goal
Casey, Scott D   +6 more
core   +4 more sources

Pain and analgesic use associated with skeletal-related events in patients with advanced cancer and bone metastases [PDF]

open access: yes, 2015
PURPOSE: Bone metastases secondary to solid tumors increase the risk of skeletal-related events (SREs), including the occurrence of pathological fracture (PF), radiation to bone (RB), surgery to bone (SB), and spinal cord compression (SCC).
A Hussain   +55 more
core   +2 more sources

Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery [PDF]

open access: yes, 2008
BACKGROUND: Intraarticular (IA) local anesthetics are often used for the management and prevention of pain after arthroscopic knee surgery. Recently, IA tramadol was also used for the management of these patients.
Baraka, Anis   +6 more
core   +2 more sources

Loss of μ-opioid receptor signaling in nociceptors, and not spinal microglia, abrogates morphine tolerance without disrupting analgesic efficacy

open access: yesNature Network Boston, 2016
Opioid pain medications have detrimental side effects including analgesic tolerance and opioid-induced hyperalgesia (OIH). Tolerance and OIH counteract opioid analgesia and drive dose escalation.
G. Corder   +10 more
semanticscholar   +1 more source

Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study [PDF]

open access: yes, 2008
<b>Objective</b>: To compare the analgesic efficacy and side effects of the synthetic cannabinoid nabilone with those of the weak opioid dihydrocodeine for chronic neuropathic pain.
Frank, B.   +4 more
core   +2 more sources

BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates [PDF]

open access: yes, 2019
© 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Background: The marked increase in mis-use of prescription opioids has greatly affected our society. One potential solution is to develop improved analgesics which have
Cami-Kobeci, Gerta   +9 more
core   +4 more sources

Prevalence and incidence of prescription opioid analgesic use in Australia

open access: yesBritish Journal of Clinical Pharmacology, 2018
The aims of the current study were to determine the prevalence and incidence of prescription opioid analgesic use in Australia and compare the characteristics of people with and without cancer initiating prescription opioid analgesics.
S. Lalic   +4 more
semanticscholar   +1 more source

Benefits of thoracic epidural analgesia in patients undergoing an open posterior component separation for abdominal herniorrhaphy [PDF]

open access: yes, 2017
INTRODUCTION: The implementation of open posterior component separation (PCS) surgery has led to improved outcomes for complex hernias. While the PCS technique has been shown to decrease recurrence rates, and provide a feasible option to repair hernias ...
Sellers, Austin
core   +1 more source

Analgesic-Like Activity of Essential Oil Constituents: An Update

open access: yesInternational Journal of Molecular Sciences, 2017
The constituents of essential oils are widely found in foods and aromatic plants giving characteristic odor and flavor. However, pharmacological studies evidence its therapeutic potential for the treatment of several diseases and promising use as ...
Rita de Cássia da Silveira e Sá   +4 more
semanticscholar   +1 more source

Progress of research on delaying bone destruction of rheumatoid arthritis by combining traditional Chinese and Western medicine

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract Rheumatoid arthritis (RA) is a common autoimmune disease with bone destruction as the core pathology, which belongs to the category of “impediment disease” in traditional Chinese medicine (TCM), and its etiology and pathogenesis are still not completely clear.
Dier Jin   +7 more
wiley   +1 more source

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