Results 21 to 30 of about 622,793 (388)

Oral application of magnesium‐L‐threonate enhances analgesia and reduces the dosage of opioids needed in advanced cancer patients—A randomized, double‐blind, placebo‐controlled trial

Cancer Medicine, 2023
Purpose To investigate the effects of oral administration of magnesium‐L‐threonate, a novel magnesium compound, on the analgesic effect of opioids in patients with advanced cancer.
Siyin Wu, Tian Jin, Bingjie Ma, Yun Ji, Xuehua Huang, Peiliang Wang, Xiaoming Liu, Boris V. Krylov, Xianguo Liu, Ke Ma   +9 more
doaj   +1 more source

Synthesis of silver and gold nanoparticles from leaf of Litchi chinensis and its biological activities

Asian Pacific Journal of Tropical Biomedicine, 2018
Objective: To synthesize and isolate silver and gold nanoparticles from Litchi chinensis leaf methanolic extract, and to evaluate its comparative biological activities including muscles relaxant, analgesic, anti-inflammatory and antidiarrheal.
Uzma Murad, Barkatullah, Shafqat Ali Khan, Muhammad Ibrar, Sami Ullah, Umbreen Khattak   +5 more
doaj   +1 more source

Pharmacogenetics of analgesic drugs [PDF]

, 2013
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R, Cregg, R, Gubbay, A, Russo, G, Sato, H   +4 more
core   +1 more source

β‐caryophyllene and β‐caryophyllene oxide—natural compounds of anticancer and analgesic properties

Cancer Medicine, 2016
Natural bicyclic sesquiterpenes, β‐caryophyllene (BCP) and β‐caryophyllene oxide (BCPO), are present in a large number of plants worldwide. Both BCP and BCPO (BCP(O)) possess significant anticancer activities, affecting growth and proliferation of ...
Klaudyna Fidyt, A. Fiedorowicz, L. Strzadala, A. Szumny   +3 more
semanticscholar   +1 more source

Evaluation of the Analgesic Effect of High-Cannabidiol-Content Cannabis Extracts in Different Pain Models by Using Polymeric Micelles as Vehicles

Molecules, 2023
Currently, cannabis is considered an attractive option for the treatment of various diseases, including pain management. Thus, developing new analgesics is paramount for improving the health of people suffering from chronic pain.
Yoreny Román-Vargas, Julián David Porras-Arguello, Lucas Blandón-Naranjo, León Darío Pérez-Pérez, Dora María Benjumea   +4 more
doaj   +1 more source

Analgesic prescribing trends in a national sample of older veterans with osteoarthritis: 2012-2017 [PDF]

, 2019
Few investigations examine patterns of opioid and nonopioid analgesic prescribing and concurrent pain intensity ratings before and after institution of safer prescribing programs such as the October 2013 Veterans Health Administration system-wide Opioid ...
Bair, Matthew J., Bean, Andrew, Brandt, Cynthia A., Brody, Abraham A., Hwang, Ula, Kerns, Robert D., Runels, Tessa, Trentalange, Mark   +7 more
core   +1 more source

Synthesis, spectral characterization, and pharmacological screening of some 4-[{1-(aryl)methylidene}-amino]-3-(4-pyridyl)-5-mercapto-4H-1,2,4-triazole derivatives

Journal of Pharmacy and Bioallied Sciences, 2010
Background : Pain is an unpleasant and subjective sensation that results from a harmful sensorial stimulation, which alerts the body about current or potential damage to its tissues and organs.
Anees A Siddiqui, Ravinesh Mishra, Rajiv Kumar, Mohd Rashid, Somila Khaidem   +4 more
doaj   +1 more source

Evaluation of Toxicity, Bacteriostatic, Analgesic, Anti-Inflammatory, and Antipyretic Activities of Huangqin-Honghua-Pugongying-Jinyinhua Extract

Veterinary Sciences, 2021
The extensive use of antibiotics has caused the global spread of multidrug-resistant bacteria and genes, seriously reducing antibiotic efficacy and threatening animal and human health. As an alternative, traditional Chinese veterinary medicine (TCVM) was
Dongyang Ye, Jing Sun, Yinqian Li
doaj   +1 more source

Cognitive impairment induced by delta9-tetrahydrocannabinol occurs through heteromers between cannabinoid CB1 and serotonin 5-HT2A receptors [PDF]

, 2015
Delta-9-tetrahydrocannabinol (THC), the main psychoactive compound of marijuana, induces numerous undesirable effects, including memory impairments, anxiety, and dependence.
A Busquets-Garcia, A Castañé, A Kern, A Manglik, A Pazos, A Pertovaara, A Zimmer, AC Magalhaes, AJ Venkatakrishnan, AL Bodor, Antoni Pastor, AR Best, Arnau Cordomí, BB Gorzalka, C Bombardi, C Castellano, C Ferrada, C Sanchis-Segura, Carmen Lluís, CP Vandermaelen, E Aso, E Fiorica-Howells, E Moreno, E Moreno, E Moreno, E Palazzo, E Puighermanal, E Puighermanal, E Valjent, Enric I. Canela, Eric J. Nestler, Estefanía Moreno, ET Weber, F Berrendero, F Rodríguez de Fonseca, F Simonin, F Steindel, FA Moreira, G Di Chiara, G Mengod, G Paxinos, G Porras, G Soria, Gemma Navarro, GM Thomas, HY Meltzer, J De Almeida, J González-Maeso, J González-Maeso, JC Parrish, JF Cheer, JF López-Giménez, JF López-Giménez, JJ Rodriguez, JM Franklin, JM Walker, JR Clapper, K Baba, K Mackie, K Monory, K Tsou, K Tsou, KA Gleason, L a. H Miner, L Callén, L Lanfumey, Laurence Lanfumey, Leonardo Pardo, Lesley A. Howell, LJ Sim-Selley, LP Martin, LTO Lee, M Bouvier, M Fribourg, M Lüttgen, M Schneider, M-M Mocanu, MJ Orejarena, N Kabli, NA Darmani, NB Eddy, NV Weisstaub, O Söderberg, P Pacher, P Rivera, Paola Gasperini, Patricia Robledo, Peter J. McCormick, R Franco, R Maldonado, R Mechoulam, R Mongeau, R Nygaard, R Schroder, Rafael de La Torre, Rafael Maldonado, RL Jakab, S Ferre, S Ferré, S Ferré, S González, S Haj-Dahmane, S Mato, S Pellow, SGF Rasmussen, SGF Rasmussen, SM Eggan, T Issad, T-W Chen, V Mendizábal, X Guitart, Xavier Viñals, Y-C Chiang   +112 more
core   +5 more sources

Chemical Composition, Analgesic and Anti-Inflammatory Activity of Pelargonium peltatum Essential Oils from Eastern Cape, South Africa

Molecules, 2023
Pelargonium species are native to South Africa, and they have a long history in medicinal use. This study aimed to extract essential oils from different parts of P.
Pamela Rungqu, Opeoluwa Oyedeji, Mavuto Gondwe, Adebola Oyedeji   +3 more
doaj   +1 more source