Results 21 to 30 of about 227,981 (244)

From Poison to Promise: The Evolution of Tetrodotoxin and Its Potential as a Therapeutic

open access: yesToxins, 2021
Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since been isolated from an array of taxa that host TTX-producing bacteria.
Gary M. Bucciarelli   +5 more
doaj   +1 more source

In Vivo, In Vitro and In Silico Study of Cucurbita moschata Flower Extract: A Promising Source of Natural Analgesic, Anti-Inflammatory, and Antibacterial Agents

open access: yesMolecules, 2023
For thousands of years, medicinal plants have played a pivotal role in maintaining human health and improving the quality of human life. This study was designed to analyze the analgesic, anti-inflammatory, and antibacterial potentials of a hydro ...
Md. Rabiul Hossain   +8 more
doaj   +1 more source

Development and optimisation of novel oral formulation of an opioid analgesic using central composite design

open access: yesCogent Medicine, 2017
Introduction of matrix type sustained release systems were a breakthrough for novel oral drug delivery systems. Present research focuses on the development and evaluation of Fentanyl citrate sustained release formulations.
Meenal M. Rane, Amrita Bajaj
doaj   +1 more source

Analgesic and Sedative Effects of Different Doses of Dexmedetomidine Combined with Butorphanol in Continuous Analgesia after a Cesarean Section

open access: yesFrontiers in Surgery, 2022
ObjectiveThe present study is designed to study the analgesic and sedative effect of different doses of dexmedetomidine combined with butorphanol in continuous analgesia after a cesarean section.MethodsA total of 60 puerperae undergoing a cesarean ...
Hui Liu   +4 more
doaj   +1 more source

Analgesic Nephropathy [PDF]

open access: yesBMJ, 1972
Sixty-six patients were seen from January 1963 to December 1970 in whom a diagnosis of analgesic nephropathy was made. The ratio of women to men was 2.7:1 and women presented at an earlier age. Over 60% of patients had or developed urinary tract infection and over one-third presented with serum urea levels over 300 mg/100 ml.
D P, Kingsley   +5 more
openaire   +2 more sources

Opioid Analgesics [PDF]

open access: yesMayo Clinic Proceedings, 2015
Chronic pain is an international health issue of immense importance that is influenced by both physical and psychological factors. Opioids are useful in treating chronic pain but have accompanying complications. It is important for clinicians to understand the basics of opioid pharmacology, the benefits and adverse effects of opioids, and related ...
Robert N, Jamison, Jianren, Mao
openaire   +2 more sources

The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo

open access: yesFrontiers in Pharmacology, 2023
Ethnopharmacological relevance: Crebanine (Cre) and Stephanine (Step) are isoquinoline aporphine-type alkaloids that are extracted from Stephania yunnanenses H. S. Lo.
Lili Cui   +8 more
doaj   +1 more source

Analgesic Effect of Morphine Added to Bupivacaine in Serratus Anterior Plane Block Following Modified Radical Mastectomy. Only a Local Effect? Randomized Clinical Trial

open access: yesJournal of Pain Research, 2020
Fatma A El Sherif,1 Ahmad M Abd El-Rahman,1 Ahmed H Othman,1 Samia A Shouman,2 Mervat M Omran,3 Nivin A Hassan,4 Sahar B Hassan,5 Ebrahim Aboeleuon6 1Anesthesia, ICU, and Pain Relief, South Egypt Cancer Institute, Assiut University, Assiut, Egypt ...
El Sherif FA   +7 more
doaj  

Comparison of antioxidant and analgesic effects of gallic acid and metformin in streptozotocin-induced hyperglycemic rats

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2023
Background and Aims: Hyperglycemia is associated with decreased activity of antioxidant enzymes and damage to peripheral nerves. The present study aimed to compare the antioxidant and analgesic effects of gallic acid (a natural compound) with metformin ...
Fatemeh Nohtani   +2 more
doaj  

Multimodal Therapies for the Treatment of Neuropathic Pain: The Role of Lidocaine Patches in Combination Therapy: A Narrative Review

open access: yesPain and Therapy
Neuropathic pain (NP) has a population presence of up to 10%. Both systemic agents and topical agents are recommended as first-line therapy for the treatment of NP but monotherapy provides adequate pain relief only in 
Srinivas Nalamachu   +5 more
doaj   +1 more source

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