Therapeutics and Clinical Risk Management, 2012 Jeffrey A GudinEnglewood Hospital and Medical Center, Englewood, NJ, USAAbstract: Prescriptions for opioid analgesics to manage moderate-to-severe chronic noncancer pain have increased markedly over the last decade, as have postmarketing reports of ...
Gudin JA
doaj
Общая реаниматология, 2014 The polymorphism of μ-opioid receptor is one of the most studied polymorphisms that affect the activity of narcotic analgesics. Despite that there are a large number of publications dealing with the problem, the obtained results are not being currently ...
V. M. Zhenilo, O. A. Makharin
doaj +1 more source
Detection of Opioid Users from Reddit Posts via an Attention-based Bidirectional Recurrent Neural Network [PDF]
The opioid epidemic, referring to the growing hospitalizations and deaths because of overdose of opioid usage and addiction, has become a severe health problem in the United States. Many strategies have been developed by the federal and local governments and health communities to combat this crisis.
arxiv +1 more source
Individual and county-level factors associated with use of multiple prescribers and multiple pharmacies to obtain opioid prescriptions in California. [PDF]
, 2012 Use of multiple prescribers and pharmacies is a means by which some individuals misuse opioids. Community characteristics may be important determinants of the likelihood of this phenomenon independent of individual-level factors. This was a retrospective
Han, Huijun +3 more
core +2 more sources
Increase in fatal poisonings involving opioid analgesics in the United States, 1999-2006 [PDF]
"KEY FINDINGS: Data from the National Vital Statistics System Mortality File. From 1999 through 2006, the number of fatal poisonings involving opioid analgesics more than tripled from 4,000 to 13,800 deaths.
National Center for Health Statistics (U.S.) Office of Analysis and Epidemiology.
core
ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy. [PDF]
, 2019 Background:Pain management with conventional opioids can be challenging due to dose-limiting adverse events (AEs), some of which may be related to the simultaneous activation of β-arrestin (a signaling pathway associated with opioid-related AEs) and G ...
Beard, Timothy L +10 more
core
National consumption of opioid and nonopioid analgesics in Croatia: 2007–2013
Therapeutics and Clinical Risk Management, 2015 Darko Krnic,1 Andrea Anic-Matic,2 Svjetlana Dosenovic,2 Pero Draganic,1 Sasa Zezelic,1 Livia Puljak2 1Agency for Medicinal Products and Medical Devices, Zagreb, 2Laboratory for Pain Research, School of Medicine, University of Split, Split, Croatia ...
Krnic D +5 more
doaj
A pharmacogenetics approach to pain management
Neuropsychopharmacology Reports, 2018 Introduction Opioid analgesics are widely used as effective analgesics for the treatment of moderate‐to‐severe pain. However, the analgesic efficacy of opioids is well known to vary widely among individuals, and effective pain treatment is hampered by ...
Kaori Yoshida +5 more
doaj +1 more source
Opioid Atlas: Mapping Access to Pain Medication [PDF]
arXiv, 2016 Opiates are some of the most effective pain relief medications available for patients suffering from cancer and surgery-related pain. Despite the affordability and effectiveness of these medications, access to opiates is highly geographically variable. Pain researchers have attributed geographic variation to various factors including the fear of opioid
arxiv
Discovering Opioid Use Patterns from Social Media for Relapse Prevention [PDF]
arXiv, 2019 The United States is currently experiencing an unprecedented opioid crisis, and opioid overdose has become a leading cause of injury and death. Effective opioid addiction recovery calls for not only medical treatments, but also behavioral interventions for impacted individuals.
arxiv