Results 111 to 120 of about 74,882 (213)
Managing Prolonged Pain After Surgery: Examining the Role of Opioids. [PDF]
A notable minority of patients experience persistent postsurgical pain and some of these patients consequently have prolonged exposure to opioids. Risk factors for prolonged opioid use after surgery include preoperative opioid use, anxiety, substance ...
Pozek, John-Paul J.+2 more
core +1 more source
Yazed AlRuthia,1,2 Hawazin Alhazzani,1 Ghaida Alhindi,1 Maryam Alarfaj,1 Lama Almutairi,3 Miteb Alanazi,4 Khaulah Alokili,1 Nouf Alanazi,1 Faris Alodaibi,5 Monira Alwhaibi,1 Adel S Bashatah,6 Yousif Asiri,1 Hisham Alsanawi7 1Department of Clinical ...
AlRuthia Y+12 more
doaj
Identifying Spatiotemporal Patterns in Opioid Vulnerability: Investigating the Links Between Disability, Prescription Opioids and Opioid-Related Mortality [PDF]
The opioid crisis remains one of the most daunting and complex public health problems in the United States. This study investigates the national epidemic by analyzing vulnerability profiles of three key factors: opioid-related mortality rates, opioid prescription dispensing rates, and disability rank ordered rates. This study utilizes county level data,
arxiv
Opiate, Opioid analgesics and antagonists
Opiate and opioid analgesics are important drugs in the treatment of pain. They are associated with addiction and respiratory depression, side effects which limit their clinical usefulness.
Milton Faccione, Dalva Trevisan Ferreira
doaj
A Multivariate Analysis of Nationwide Changes in Opioid Prescriptions from 2012-2016 [PDF]
Background Between 2012 and 2016, the opioid overdose mortality rate in the U.S. almost doubled from 7.4 to 13.3 per 100,000 population, leading to calls for a national opioid crisis. This crisis has generated interest in Medicaid’s dual role as a health
Ku, Leighton, Pillai, Drishti
core +1 more source
The atomistic level structure for the activated human κ-opioid receptor bound to the full Gi protein and the MP1104 agonist [PDF]
The kappa opioid receptor (κOR) is an important target for pain therapeutics to reduce depression and other harmful side effects of existing medications.
Goddard, William A., III+2 more
core +1 more source
Role of Dentists in Prescribing Opioid Analgesics and Antibiotics: An Overview [PDF]
Ackerman+99 more
core +2 more sources
Medicines based on opioid analgesics are the basic means of pharmacotherapy of severe pain at present. Approaches to increase efficacy and safety of complex opioid analgesia are described and classified based on analysis of medicinal and veterinary ...
A. V. Sosnov+4 more
doaj
Investigating the importance of social vulnerability in opioid-related mortality across the United States [PDF]
The opioid crisis remains a critical public health challenge in the United States. Despite national efforts to reduce opioid prescribing rates by nearly 45\% between 2011 and 2021, opioid overdose deaths more than tripled during this same period. This alarming trend reflects a major shift in the crisis, with illegal opioids now driving the majority of ...
arxiv