Results 131 to 140 of about 62,166 (293)
Assessing benefits and harms of opioid therapy for chronic pain [PDF]
Clinician Outreach and Communication Activity (COCA) conference call Wednesday, August 3, 2016.Although evidence supports short-term effectiveness of opioids to treat pain, there is insufficient data that long-term use of opioids effectively treats ...
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Codeine and Metabolite Concentrations in the Breastfed Neonate
Pediatric Anesthesia, EarlyView.ABSTRACT Analgesic effect from codeine is from its metabolite, morphine. Morphine is formed by the O‐demethylation of codeine and that enzyme is controlled by the cytochrome P450 2D6. More than 60 alleles in the CYP2D6 gene have been identified. This spectrum of polymorphism can be categorized into four groups: poor (PM), intermediate (IM), normal (NM),
Brian J. Anderson, Jacqueline A. Hannam
wiley +1 more source
Current pharmacology of Opioid Analgesics in Cancer related Chronic Pain
Pain is one of the major symptoms that cancer patients suffer from before, during and even after treatment. The mainstay of pain management for cancer patients is the administration of opioid analgesics.
Mabika, Rosina
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Pediatric Anesthesia, EarlyView.ABSTRACT Objective To conduct a meta‐analysis of postoperative outcomes following the use of regional anesthesia in pediatric cardiac surgery. Data Sources We searched PubMed (MEDLINE), Web of Science, CINAHL, CENTRAL, and Scopus in December 2024 (PROSPERO: CRD420025635423; registered January 2025).
Katariina Hiisivuori +3 more
wiley +1 more source
Multimodal Treatment of Neck Pain in Multiple System Atrophy
Movement Disorders Clinical Practice, EarlyView.
Bianca Caliò +2 more
wiley +1 more source
Pediatric Anesthesia, EarlyView.ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles +3 more
wiley +1 more source
OPIOID DEATHS IN CONSTRUCTION [Spanish]
OPIOID DEATHS IN CONSTRUCTION [Spanish]Opioids-Hazard-Alert-Spanish.pdfproducci\uf3n de este documento fue respaldada por el acuerdo cooperativo OH 009762 del Instituto Nacional de Seguridad y Salud Ocupacional ...
core +1 more source
Understanding the opioid overdose epidemic [PDF]
The number of drug overdose deaths increased by nearly 30% from 2019 to 2020 and has quintupled since 1999. Nearly 75% of the 91,799 drug overdose deaths in 2020 involved an opioid.
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Pediatric Anesthesia, EarlyView.ABSTRACT Background Objective assessment of sedation depth in children undergoing procedural sedation while maintaining spontaneous breathing and protective reflexes can be challenging. Processed electroencephalogram (pEEG) monitoring systems such as the Narcotrend monitor may provide continuous information regarding the depth of sedation.
Hendryk Schneider +3 more
wiley +1 more source
Pediatric Anesthesia, EarlyView.ABSTRACT Introduction Emergence agitation (EA) is a postoperative neurobehavioral complication characterized by a transient disturbance in cognition and perception following anesthesia. Neuroinflammation is thought to play a central role in its pathophysiology.
Nezahat Merve Ata Soylu +6 more
wiley +1 more source