Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud +4 more
wiley +1 more source
Health, Social and Recidivism Outcomes Among People Who Have Been Incarcerated in New South Wales, Australia: Study Protocol and Cohort Profile for the Prison Outcomes STudy (POST). [PDF]
Degenhardt L +19 more
europepmc +1 more source
Addressing the prescription opioid crises : CDC Rx Awareness campaign overview
To raise awareness of prescription opioid abuse and overdose, in 2017 the Centers for Disease Control and Prevention (CDC) launched Rx Awareness, its first prescription opioid overdose prevention campaign. The Rx Awareness campaign is evidence-driven and
core
Addressing the unique challenges of opioid use disorder in women [PDF]
Tuesday, January 17, 2017 at 1 p.m. ESTDeaths from drug overdoses are the number one cause of injury death in the U.S. Most of these deaths are related to the misuse of prescription opioids and heroin.
core
Purpose: This study aimed to determine the median effective volume (EV50) of 0.2% ropivacaine for ultrasound‐guided axillary brachial plexus block (ABPB) in children aged 6–10 years, using the Dixon up‐and‐down method. The EV50 was 0.350 mL/kg (95% CI: 0.197–0.362 mL/kg), calculated by isotonic regression and bootstrapping.
Tauseef Ahmad +11 more
wiley +1 more source
Pain and Prose: Tracing the Opioid Epidemic in Stephen King's Novels. [PDF]
Marquez-Romero JM.
europepmc +1 more source
Connections between MSDs and Prescription Opioid Use in Construction
Musculoskeletal Disorders and Prescription Opioid Use among U.S. Construction WorkersXiuwen Sue Dong, Raina D. Brooks, and Samantha Brown. Journal of Occupational and Environmental Medicine, 2020.J Occup Environ Med. 2020 Nov;62(11):973-979. doi: 10.1097/
core
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager +3 more
wiley +1 more source
High-Frequency Global Postoperative Status PROMs Track Pain Peaks and Analgesic Use After Degenerative Lumbar Spine Surgery. [PDF]
Lenga P +6 more
europepmc +1 more source
Secular trends in opioid prescribing in the USA
Edmund J Pezalla,1 David Rosen,2 Jennifer G Erensen,2 J David Haddox,2,3 Tracy J Mayne2 1Bioconsult, LLC, Wethersfield, 2Purdue Pharma L.P., Stamford, CT, 3Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA ...
Haddox JD +4 more
core

