Results 191 to 200 of about 87,386 (292)

Prevalence of acute pain crisis in patients with cancer in Specialist Palliative Care Clinic: An observational study. [PDF]

BMC Palliat Care
Kamble S, Thota RS, Poojary S, Deodhar J, M VT, Shah IJ, Ajith A.   +6 more
europepmc   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

Non-Pharmacological Option in Postoperative Pain: Pilot Study of Intraoperative Pulsed Radiofrequency. [PDF]

Interdiscip Cardiovasc Thorac Surg
Kumagai R, Kabemura S, Kojima F, Nobuko F, Bando T.   +4 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Prescription Monitoring Program Mandates and Opioids Dispensed to Patients Dying of Cancer. [PDF]

JCO Oncol Pract
Bao Y, Zhang H, Pinheiro LC, Hu JC, Portenoy RK, Bruera E, Reid MC, Tamimi RM, Zhang F, Zhang Y, Paice JA, Rosa WE.   +11 more
europepmc   +1 more source

Good Practice in Postoperative and Procedural Pain Management 2nd Edition [PDF]

, 2012
CARTER, BERNIE, Curry, Joe, Howard, Richard, Jain, Anoo, Liossi, Christina, Morton, Neil, Rivett, Kate, Rose, Mary, Tyrell, Jennifer, Walker, Suellen, Williams, Glynn   +10 more
core  

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Postoperative Pain Management in Patients with Lower-Extremity Amputations: A Single-Institution Retrospective Analysis of the Effectiveness of Non-opioid Analgesics in Reduction of Opioid Use. [PDF]

Cureus
Dinh CH, Park HA, Vassantachart AY, Manhas NS, Tran DA, Pak E.   +5 more
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Postoperative opioid-free analgesia with acetaminophen and its impact on pain and postoperative nausea and vomiting following arthroscopic rotator cuff repair: a single-center retrospective study. [PDF]

J Pharm Health Care Sci
Okizuka M, Inose R, Maruoka S, Takeuchi M, Hirotsu S, Nakamura M, Muraki Y.   +6 more
europepmc   +1 more source