Results 201 to 210 of about 87,386 (292)

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini, Riccardo Camilotto, Michele Maritan, Erika Morrone, Stephen Afriyie Boateng, Anna Vacilotto, Salvatore Pacifico, Remo Guerrini, Nurulain T. Zaveri, Girolamo Calo'   +9 more
wiley   +1 more source

Efficacy and Harms of Opioid Analgesics for Acute Pain: Overview of Systematic Reviews and Meta-analyses. [PDF]

Drugs
Mathieson S, Zadro JR, Narayan SW, McLachlan AJ, Ballantyne JC, Blyth FM, Day RO, Maher CG, McLachlan H, Lin CC, Kamper SJ, Abdel Shaheed C.   +11 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Pharmacogenomics and Opioid Efficacy in Sickle Cell Disease. [PDF]

Medicina (Kaunas)
Elshaikh RH, Babker AM, Hussein SE, Ahmed KAM, Sah AK, Alfeel AH.   +5 more
europepmc   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli, Deborah Rudin, Dino Luethi, Matthias E. Liechti, Sabrine Bilel, Matteo Marti, Henrik Green, Manuela Carla Monti, Caitlyn Norman   +8 more
wiley   +1 more source

Review of Risk Factors for Opioid Misuse and Addiction Following Traumatic Injury. [PDF]

Healthcare (Basel)
Lawler NJ, Sobhani B, Salihu EY, Muller H, Edwards J, Ringo M, Brown R.   +6 more
europepmc   +1 more source

[Opioid analgesics].

Vojnosanitetski pregled, 2004
Sonja, Vucković, Milica, Prostran, Milovan, Ivanović, Zoran, Todorović, Radan, Stojanović, Zorica, Nesić, Ivana, Matić, Slobodan, Milovanović   +7 more
openaire   +1 more source

Platelet‐Rich Fibrin Can Improve Septoplasty Results: A Prospective Randomised Controlled Trial

Clinical Otolaryngology, EarlyView.
ABSTRACT Aim This study aims to assess the impact of platelet‐rich fibrin (PRF) on nasal mucociliary clearance (NMC) time and post‐operative pain following septoplasty. Patients and Methods This trial was conducted involving patients who underwent septoplasty. Participants were randomly assigned to either a control group or a PRF group.
Emre Solguntekin, Sedat Çağlı, Kerem Kökoğlu, Emrah Gülmez   +3 more
wiley   +1 more source

Is There an Allergy to Pure Metallic Gold Micro‐Particles?—An Epicutaneous Study of Gold Micro‐Particles, Gold Thiosulphate, and Placebo

Contact Dermatitis, EarlyView.
In an epicutaneous test, no allergic reactions were observed in response to pure metallic gold particles. ABSTRACT Background Previous studies investigating gold allergy have used gold thiosulphate (GCST) rather than pure gold, reporting an incidence up to 30%. Objectives As it is unclear whether these reactions are due to ions from pure gold or solely
Sten Rasmussen, Peter Bjerring
wiley   +1 more source