Results 21 to 30 of about 86,963 (292)
BMJ Open, 2020 Objectives Many central nervous system (CNS) medications are considered potentially inappropriate for prescribing in older people; however, these medications are common in polypharmacy (≥5 medicines) regimens.
Natasha Slater +2 more
doaj +1 more source
Frontiers in Psychiatry, 2022 BackgroundOwing to their pharmacological properties the use of opioid analgesics carries a risk of abuse and dependence, which are associated with a wide range of personal, social, and medical problems.
Christian Rauschert +8 more
doaj +1 more source
Opioid Analgesic Prescribing Practices of Dental Professionals in the United States [PDF]
, 2017 The prescription of opioid analgesics by dental professionals is widespread in the United States. Policy makers, government agencies, and professional organizations consider this phenomenon a growing public health concern.
Okunseri, Christopher +4 more
core +2 more sources
Changes in analgesic strategies for lobectomy from 2009 to 2018Central MessagePerspective
JTCVS Open, 2021 Objective: To evaluate trends in the use of epidural analgesia and nonopioid and opioid analgesics for patients undergoing lobectomy from 2009 to 2018.
Theresa Lo, MD +9 more
doaj +1 more source
The unsolved case of “bone-impairing analgesics”. The endocrine effects of opioids on bone metabolism [PDF]
, 2015 The current literature describes the possible risks for bone fracture in chronic analgesics users. There are three main hypotheses that could explain the increased risk of fracture associated with central analgesics, such as opioids: 1) the increased ...
COLUZZI, FLAMINIA +3 more
core +3 more sources
Safety of opioid patch initiation in Australian residential aged care [PDF]
, 2015 Explores opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Abstract Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design:
Elizabeth Roughead +2 more
core +1 more source
In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]
, 2018 Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta +4 more
core +2 more sources
Recent Chemical and Pharmacological Developments on 14-Oxygenated-N-methylmorphinan-6-ones
Molecules, 2021 Adequate pain management, particularly chronic pain, remains a major challenge associated with modern-day medicine. Current pharmacotherapy offers unsatisfactory long-term solutions due to serious side effects related to the chronic administration of ...
Mariana Spetea, Helmut Schmidhammer
doaj +1 more source
Prague Medical Report, 2013 The aim of prospective study was to evaluate the pain relief in the postoperative period and consumption of opioid and non-opioid analgesics as a risk factor of the anastomotic insufficiency after rectal and rectosigmoideal resection for carcinoma ...
S. Adámek +5 more
doaj +1 more source
Analgesic prescribing trends in a national sample of older veterans with osteoarthritis: 2012-2017 [PDF]
, 2019 Few investigations examine patterns of opioid and nonopioid analgesic prescribing and concurrent pain intensity ratings before and after institution of safer prescribing programs such as the October 2013 Veterans Health Administration system-wide Opioid ...
Bair, Matthew J. +7 more
core +1 more source