Results 21 to 30 of about 392,664 (239)

Recent Chemical and Pharmacological Developments on 14-Oxygenated-N-methylmorphinan-6-ones

Molecules, 2021
Adequate pain management, particularly chronic pain, remains a major challenge associated with modern-day medicine. Current pharmacotherapy offers unsatisfactory long-term solutions due to serious side effects related to the chronic administration of ...
Mariana Spetea, Helmut Schmidhammer
doaj   +1 more source

The Effect of Postoperative Pain Treatment on the Incidence of Anastomotic Insufficiency after Rectal and Rectosigmoideal Surgery

Prague Medical Report, 2013
The aim of prospective study was to evaluate the pain relief in the postoperative period and consumption of opioid and non-opioid analgesics as a risk factor of the anastomotic insufficiency after rectal and rectosigmoideal resection for carcinoma ...
S. Adámek, Olga Matoušková, O. Polanecký, S. Světlík, J. Skořepa, M. Šnajdauf   +5 more
doaj   +1 more source

Gamma‐aminobutyric acid transaminase genetic polymorphism is a candidate locus for responsiveness to opioid analgesics in patients with cancer pain: An exploratory study

Neuropsychopharmacology Reports, 2018
Aim Cancer pain impairs not only physical functions but also social functions and roles. Consequently, the overall health‐related quality of life of patients with cancer pain deteriorates. Opioid analgesics are recommended for treating moderate to strong
Yaeko Yokoshima, Masahiko Sumitani, Daisuke Nishizawa, Makoto Nagashima, Kazutaka Ikeda, Ryoji Kato, Jun Hozumi, Hiroaki Abe, Kenji Azuma, Rikuhei Tsuchida, Yoshitsugu Yamada, Japanese TR‐Cancer Pain Research Group   +11 more
doaj   +1 more source

Clinically important drug interactions with opioid and non-opioid analgesics [PDF]

Arhiv za farmaciju, 2018
Patients often seek advise from doctors and pharmacists about pain treatment. Opioid and non-opioid analgesics are the most commonly used drugs in the treatment of pain, but they have potential for pharmacodynamic and pharmacokinetic drug-drug ...
Vezmar-Kovačević Sandra, Vučićević Katarina, Vučenović-Topić Valentina, Rajkovača Zvezdana, Miljković Branislava   +4 more
doaj   +1 more source

Novel Synthetic Opioids (NSO) Use in Opioid Dependents Entering Detoxification Treatment

Frontiers in Psychiatry, 2022
IntroductionOver the last decade, the use of New/Novel Synthetic Opioids (NSO) has emerged as an increasing problem, and especially so in the USA. However, only little is known about the prevalence and history of NSO use in European heroin dependents ...
Michael Specka, Thomas Kuhlmann, Udo Bonnet, Jürgen Sawazki, Luzia Schaaf, Stefan Kühnhold, Renate Steinert, Torsten Grigoleit, Helmut Eich, Benita Zeiske, Antje Niedersteberg, Katharina Steiner, Fabrizio Schifano, Norbert Scherbaum   +13 more
doaj   +1 more source

The effect of opioid analgesics, benzodiazepines, gabapentinoids, and opioid agonist treatment on mortality risk among opioid-dependent people.

International Journal of Population Data Science, 2022
Background As dispensings for benzodiazepines and gabapentinoids have increased in recent years, risk of increased mortality has been identified, particularly when used with opioids. There is limited research examining use of these medicines among people
Chrianna Bharat, Natasa Gisev, Sebastiano Barbieri, Tim Dobbins, Sarah Larney, Michael Farrell, Louisa Degenhardt   +6 more
doaj   +1 more source

Patient-Centered Reduction or Discontinuation of Long-term Opioid Analgesics: The HHS Guide for Clinicians.

Journal of the American Medical Association (JAMA), 2019
Discontinuation of Long-term Opioid Analgesics was responsible for developing the HHS Guide for Clinicians on the Appropriate Dosage Reduction or Discontinuation of Long-Term Opioid Analgesics. Deborah (US Centers for and Christopher PharmD, DrPH and MPE
D. Dowell, W. Compton, B. Giroir
semanticscholar   +1 more source

Prescribing and administration of opioid analgesics in residents of aged care facilities

Journal of Research in Pharmacy Practice, 2019
Objective: Optimal pain management in residents requires an understanding of prescribing and administration of opioid analgesics. This study aimed to describe opioid administration for elderly residents in a selection of aged care facilities.
Areej Numan Hussein, Lynne Emmerton
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Predictors of shortages of opioid analgesics in the US: Are the characteristics of the drug company the missing puzzle piece?

PLoS ONE, 2021
BackgroundShortages of opioid analgesics are increasingly common, interfere with patient care and increase healthcare cost. This study characterized the incidence of shortages of opioid analgesics in the period 2015-2019 and evaluated potential ...
Rosa Rodriguez-Monguio, Mahim Naveed, Enrique Seoane-Vazquez   +2 more
doaj   +1 more source