The trends in opioid use in Castile and Leon, Spain: A population-based registry analysis of dispensations in 2015 to 2018 [PDF]
, 2019 Producción CientíficaOpioids are driving-impairing medicines (DIM). To assess the evolution and trends of opioid analgesics use between 2015 and 2018 in Castile and Leon (Spain), a population-based registry study was conceived.
Ayestarán, Ignacio +4 more
core +1 more source
Opioid Analgesics in the Management of Neuropathic Pain
Pain Research and Management, 2000 The role of antidepressants and anticonvulsants in the management of neuropathic pain has been well established. However, up to 50% of patients obtain inadequate pain relief with the use of either or both of these agents; in this subpopulation, an opioid
Dwight Moulin
doaj +1 more source
Geographic Spillover Effects of Prescription Drug Monitoring Programs (PDMPs) [PDF]
arXiv, 2021 Prescription Drug Monitoring Programs (PDMPs) seek to potentially reduce opioid misuse by restricting the sale of opioids in a state. We examine discontinuities along state borders, where one side may have a PDMP and the other side may not. We find that electronic PDMP implementation, whereby doctors and pharmacists can observe a patient's opioid ...
arxiv
Opioid and Nonopioid Analgesic Prescriptions for Dental Visits in the Emergency Department, 2015-2017 National Hospital Ambulatory Medical Care Survey [PDF]
, 2021 Introduction: Prescription and nonprescription opioid misuse and the rising number of dental visits in emergency departments (EDs) are growing public health concerns in the US.
Kelekar, Uma +2 more
core +2 more sources
Медицина болю, 2020 The current strategy of rational perioperative analgesia involves reducing the use of opioid analgesics and preventing associated side effects. Today it is known that the use of opioid analgesics can further lead to the development of hyperalgesia ...
Dmytro Dmytriiev +4 more
doaj +1 more source
Acute Pain, 2008 Although there is no “ideal analgesic,” scientists and clinicians alike continue to search for compounds with qualities which may approach the “ideal analgesic.” Characteristics of an “ideal” analgesic may include: the agent is a full agonist providing optimal/maximal analgesia for a wide range/variety of pain states (e.g., broad spectrum analgesic ...
openaire +4 more sources
Trends in long-term prescribing of dependence forming medicines [PDF]
, 2019 Using patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time.
McManus, S. +3 more
core
Quantitative Systems Pharmacology and Biased Agonism at Opioid Receptors: A Potential Avenue for Improved Analgesics [PDF]
, 2022 Chronic pain is debilitating and represents a significant burden in terms of personal and socio-economic costs. Although opioid analgesics are widely used in chronic pain treatment, many patients report inadequate pain relief or relevant adverse effects,
Baiula M. +3 more
core +1 more source
Changes in analgesic strategies for lobectomy from 2009 to 2018Central MessagePerspective
JTCVS Open, 2021 Objective: To evaluate trends in the use of epidural analgesia and nonopioid and opioid analgesics for patients undergoing lobectomy from 2009 to 2018.
Theresa Lo, MD +9 more
doaj
Pharmacogenetics of analgesic drugs [PDF]
, 2013 • Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R +4 more
core +1 more source