Results 91 to 100 of about 52,277 (300)

Obtainment of prescribed analgesics among patients with Lyme neuroborreliosis; a nationwide, population-based matched cohort study

Ticks and Tick-Borne Diseases
Background: Radicular pain is the most predominant symptom among adults with Lyme neuroborreliosis (LNB) but the duration preceding and following diagnosis remains unknown.
Malte M. Tetens, Nanna S. Andersen, Ram B. Dessau, Svend Ellermann-Eriksen, Charlotte Sværke Jørgensen, Michael Pedersen, Jacob Bodilsen, Kirstine K. Søgaard, Jette Bangsborg, Alex Christian Yde Nielsen, Jens Kjølseth Møller, Niels Obel, Anne-Mette Lebech, Lars Haukali Omland   +13 more
doaj   +1 more source

Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose

Drug Testing and Analysis, EarlyView.
A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek, Marie Katrine Klose Nielsen, Robert Kronstrand, Sys Stybe Johansen   +3 more
wiley   +1 more source

Opioids for newborn infants receiving mechanical ventilation

, 2020
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the benefits and harms of opioid analgesics in neonates (term or preterm) receiving mechanical ventilation, compared to placebo, no drug ...
Romantsik, Olga, de Waal, Koert A., Bellù, Roberto, Zanini, Rinaldo,, Romantsik, Olga,, de Waal, Koert A.,, Nava, Chiara, Bellù, Roberto,, Zanini, Rinaldo, Bruschettini, Matteo,, Lund University., Bruschettini, Matteo, Nava, Chiara,   +12 more
core   +1 more source

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene

Drug Testing and Analysis, EarlyView.
Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger   +6 more
wiley   +1 more source

Use of analgesics before and after total joint replacement in working-age Japanese patients with knee and hip osteoarthritis: A retrospective database study

Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology
Background: Patterns of analgesic use before and after total joint replacement (TJR) in patients with knee/hip osteoarthritis (OA) is not well reported.
Nozomi Ebata, Takashi Sakai, Hiroyuki Yamamoto, Tetsumi Toyoda, Kanae Togo, Masataka Deie   +5 more
doaj   +1 more source

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

Drug Testing and Analysis, EarlyView.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler, Tobias Veit, Thomas Keller, Volker Auwärter   +3 more
wiley   +1 more source

Global Trends and Insights Into Opioid Utilization for Postoperative Pain Management: A Bibliometric Analysis (2014–2024)

Pain Research and Management
Conclusion: This bibliometric analysis mapped the scientific landscape of opioids in postoperative analgesia. The research hotspots included importance of complications management, nonopioid analgesics, clinical validation of OFA, and pharmacokinetics of
Lingxian Kong, Jiangang Hu
doaj   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee, Rachel C. Hector, Lynn Pezzanite, Eric Gilleland, Marlis L. Rezende   +4 more
wiley   +1 more source

Opioid and Adjuvant Analgesics: Compared and Contrasted

, 2011
An adjuvant (or co-analgesic) is a drug that in its pharmacological characteristic is not necessarily primarily identified as an analgesic in nature but that has been found in clinical practice to have either an independent analgesic effect or additive ...
Norman Brito-Dellan, Mohammed Ilyas Ahmed Khan, Declan Walsh   +2 more
core   +1 more source

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

Equine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla, José I. Redondo, Polly M. Taylor, Luis Domenech, Javier Doménech, Gordon Mark Johnston, Regula Bettschart‐Wolfensberger   +6 more
wiley   +1 more source