Results 71 to 80 of about 120,626 (262)

Impact of parameter settings on the estimation of drug exposure with the individualized dispensing patterns method

British Journal of Clinical Pharmacology, EarlyView.
Aim To assess the impact of parameter settings when using the individualized dispensing patterns (IDP) method to estimate exposure duration from dispensing data. Methods We conducted a cohort study using a 2% representative sample of the French healthcare insurance database from 2013 to 2022.
Laëtitia Gosselin, Clara Lévy, Noémie Sève, Thierry Blanchon, Marianne Sarazin, Louise Rossignol, Maryse Lapeyre‐Mestre, Nathanaël Lapidus, Olivier Steichen   +8 more
wiley   +1 more source

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source

Paediatric clonidine medication errors: Findings from a multicentre French study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to describe the characteristics of medication errors involving clonidine in paediatric patients and reported to French Network of Pharmacovigilance and Poison Control Centres. Methods This retrospective observational study analysed clonidine‐related medication errors reported between 1985 and June 2024 in patients under 12 years ...
Eve‐Marie Thillard, Anthony Facile, Marion Lepelley, Morgane Cellier, Laurent Chouchana, Sophie Gautier, Ramy Azzouz, Thierry Vial, Annie‐Pierre Jonville‐Bera   +8 more
wiley   +1 more source

Analgesic Administration for Patients with Renal Colic in the Emergency Department Before and After Implementation of an Opioid Reduction Initiative

Western Journal of Emergency Medicine, 2018
Introduction: We aimed to evaluate the patterns of analgesic prescribing for emergency department (ED) patients suffering from pain of renal colic before, during, and after implementation of an opioid reduction initiative.
Sergey Motov, Jefferson Drapkin, Mahlaqa Butt, Andrew Thorson, Antonios Likourezos, Peter Flom, John Marshall   +6 more
doaj   +1 more source

Prescribed Analgesics.

, 2015
Number of Good and Mild responders on daily use of prescribed analgesics. Tramadol, Codeine and Buprenorphine are opioids, while Duloxetine and Pregabalin are approved for the management of neuropathic pain.
Michael Matousek (202832), Lena Halaouate (728318), Carl-Gerhard Gottfries (202835), Sara Forsmark (728317), Olof Zachrisson (58616), Birgitta Peilot (728319), Björn Regland (728316)   +6 more
core   +1 more source

A longitudinal cohort study on dispensed analgesic and psychotropic medications in older adults before, during, and after the COVID-19 pandemic: the HUNT study

BMC Geriatrics
Background There is a growing concern and debate over the inappropriate use of analgesics and psychotropic medications by older adults, especially those with dementia.
Tanja Louise Ibsen, Ekaterina Zotcheva, Sverre Bergh, Debby Gerritsen, Gill Livingston, Hilde Lurås, Svenn-Erik Mamelund, Anne Marie Mork Rokstad, Bjørn Heine Strand, Richard C. Oude Voshaar, Geir Selbæk   +10 more
doaj   +1 more source

Pain therapy in patients with musculoskeletal disorders in outpatient setting: A cohort study

Cogent Medicine, 2016
Objectives: The aim was to determine the habits of physical medicine and rehabilitation specialists (PRM) in the prescription of analgesics and application of different physical modalities in outpatients, and to investigate if there are any differences ...
Stefan Kostadinović, Jovan Vasiljević
doaj   +1 more source

Pharmacology of opioids as a drug of abuse

, 2020
The object of this thesis is to review the pharmacology of opioids as drugs of abuse. It focuses on the pharmacology of opioids, its antagonist, naloxone, and their use in the current rise in opioid related overdoses.
Eiríksdóttir, Ríkey
core  

Gabapentin as an add‐on analgesic to morphine in paediatric patients with chronic pain

British Journal of Clinical Pharmacology, EarlyView.
Aims Off‐label use of gabapentin for the treatment of chronic pain in children has increased over the last decade, with multiple clinical trials evaluating its role pain management and potential opioid‐sparing effects. To date, however, these studies appear to rely on empirical evidence without further consideration of pharmacokinetic‐pharmacodynamic ...
Paul Healy, Mariagrazia Felisi, Adriana Ceci, Oscar Della Pasqua, on Behalf of the GAPP Consortium, Corinne Alberti, Donato Bonifazi, Adriana Ceci, Thomas G. de Leeuw, Saskia N. de Wildt, Mariagrazia Felisi, Florentia Kaguelidou, Enora Le Roux, Rebecca Lundin, Laura Mangiarini, Dick Tibboel   +15 more
wiley   +1 more source

Overuse of the psychoactive analgesics' opioids and gabapentinoid drugs in patients having surgery for nerve entrapment disorders. [PDF]

Sci Rep, 2023
Dahlin LB, Perez R, Nyman E, Zimmerman M, Merlo J.   +4 more
europepmc   +1 more source