Results 61 to 70 of about 120,626 (262)

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

An Investigation of Safety and Efficacy of Intravenous Paracetamol in Pain Management Following Cardiac Surgery [PDF]

open access: yesJournal of Cardio-Thoracic Medicine, 2015
Introduction: Optimum pain management immediately after surgeries can lower the possibility of pain syndrome and its following consequences. Opioids are amongst the analgesics used for postoperative pain control; however, their application can bring ...
Ehsan Mahdavi   +2 more
doaj  

Different methods of pain relief for IVF and ICSI oocyte retrieval – A Dutch survey

open access: yesEuropean Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2019
Objective: Which analgesia methods are used during oocyte retrieval in the Netherlands? StudyDesign: In April 2017, an online survey containing questions on the analgesia protocol used for IVF/ICSI oocyte retrieval was sent to all clinics in the ...
Inez Roest   +3 more
doaj   +1 more source

Precision medicine in paediatrics: Progress and priorities

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain   +3 more
wiley   +1 more source

Digital Analgesic Comprising a Second-Generation Digital Health System: Increasing Effectiveness by Optimizing the Dosing and Minimizing Side Effects

open access: yesJournal of Pain Research, 2022
Henny Azmanov,* Areej Bayatra,* Yaron Ilan Hebrew University, Faculty of Medicine, Hadassah Medical Center, Jerusalem, Israel*These authors contributed equally to this workCorrespondence: Yaron Ilan, Department of Medicine, Hebrew University,
Azmanov H, Bayatra A, Ilan Y
doaj  

Analgesic prescribing for patients discharged from an orthopaedic department: Analgesic prescribing for orthopaedic patients [PDF]

open access: yesSerbian Journal of Anesthesia and Intensive Therapy, 2016
Introduction: Uncontrolled postoperative pain is a major problem for functional recovery after orthopedic surgery. There is evidence that following patient discharge, moderate to severe pain is commonly reported early on and later in the postoperative ...
Selaković Ivan   +5 more
doaj   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili   +6 more
wiley   +1 more source

PROSPECTS OF USING A COMBINATION OF LOCALLY INJECTED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS AND OPIOIDS IN PERIPHERAL PAIN MANAGEMENT

open access: yesВестник анестезиологии и реаниматологии, 2019
The article reviews scientific literature on serious side effects of non-steroidal anti-inflammatory drugs (NSAIDs) and opioid analgesics widely used to treat acute and chronic pain.
YU. А. KOLESNIKOV
doaj   +1 more source

Pharmacotherapy of cancer pain with opioid analgesics [PDF]

open access: yesHospital Pharmacology, 2023
Introduction: Selection of analgesics should be based on the World Health Organization (WHO) analgesic ladder, beginning with non-opioid analgesics in combination with adjuvants for mild pain, weak opioids with adjuvants are indicated for moderate pain ...
Krtinić Dane A.   +15 more
doaj  

Opioids

open access: yes, 2010
Opioid receptor structure and function can be altered in neuropathic pain states, leading to reduced sensitivity to opioids Opioids were thought to be ineffective for neuropathic pain but substantial
Michael I. Bennett
core   +1 more source

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