Results 11 to 20 of about 73,043 (295)

Predictors of the use of analgesic drugs 1 year after joint replacement: a single-center analysis of 13,000 hip and knee replacements

Arthritis Research & Therapy, 2020
Background Pain persists in a moderate number of patients following hip or knee replacement surgery. Persistent pain may subsequently lead to the prolonged consumption of analgesics after surgery and expose patients to the adverse drug events of opioids ...
Tuomas Jaakko Rajamäki, Pia A. Puolakka, Aki Hietaharju, Teemu Moilanen, Esa Jämsen   +4 more
doaj   +1 more source

A diencephalic circuit in rats for opioid analgesia but not positive reinforcement

Nature Communications, 2022
Opioids are potent analgesics but also have addiction risk. Here a lateral preoptic area to lateral habenula connection is identified by which opioids relieve ongoing pain but do not produce reward in animals that do not have ongoing pain.
Maggie W. Waung, Kayla A. Maanum, Thomas J. Cirino, Joseph R. Driscoll, Chris O’Brien, Svetlana Bryant, Kasra A. Mansourian, Marisela Morales, David J. Barker, Elyssa B. Margolis   +9 more
doaj   +1 more source

Individual and county-level factors associated with use of multiple prescribers and multiple pharmacies to obtain opioid prescriptions in California. [PDF]

, 2012
Use of multiple prescribers and pharmacies is a means by which some individuals misuse opioids. Community characteristics may be important determinants of the likelihood of this phenomenon independent of individual-level factors. This was a retrospective
Han, Huijun, Kass, Philip, Li, Chin-Shang, Wilsey, Barth   +3 more
core   +7 more sources

Opioid Analgesic Prescribing Practices of Dental Professionals in the United States [PDF]

, 2017
The prescription of opioid analgesics by dental professionals is widespread in the United States. Policy makers, government agencies, and professional organizations consider this phenomenon a growing public health concern.
Okunseri, Christopher, Okunseri, Elaye, Steinmetz, C. N., Szabo, Aniko, Zheng, C.   +4 more
core   +2 more sources

Addressing the Global Tragedy of Needless Pain: Rethinking the United Nations Single Convention on Narcotic Drugs [PDF]

, 2007
The lack of medical availability of effective pain medication is an enduring and expanding global health calamity. Despite important medical advances, pain remains severely under-treated worldwide, particularly in developing countries.
Allyn L. Taylor, Birnie, Chayes, Cole, De Lima, Farmer, Foley, Joranson, Raustiala, Scholten, Szasz, Taylor   +11 more
core   +2 more sources

Management of pain treatment in the early postoperative period. Practice of using ketorolac. A clinical case

Медицина болю, 2020
The current strategy of rational perioperative analgesia involves reducing the use of opioid analgesics and preventing associated side effects. Today it is known that the use of opioid analgesics can further lead to the development of hyperalgesia ...
Dmytro Dmytriiev, A Andriiets, E Andriiets, V Bankivsky, S Yatsenko   +4 more
doaj   +1 more source

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]

, 2015
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh, Eva Saar, Jennifer Pilgrim, Louisa Degenhardt, Lucinda Burns, Suzanne Nielsen, Wayne D Hall   +6 more
core   +1 more source

Healthcare professionals’ perceptions on the use of opioid analgesics for the treatment of cancer-related pain in Cyprus: A mixed-method study

SAGE Open Medicine, 2019
Objectives: Pain is considered the most common and debilitating symptom reported by patients affected by cancer, and opioids are at the front line for its effective management.
Andreas Charalambous, Marios Zorpas, Constantina Cloconi, Yolanda Kading   +3 more
doaj   +1 more source

Effects of long-term opioid analgesics on cognitive performance and plasma cytokine concentrations in patients with chronic low back pain: a cross-sectional pilot study

PAIN Reports, 2018
. Introduction:. Cognitive performance and inflammation are altered in people with chronic low back pain (CLBP). Yet, the magnitude of these changes has been unclear because of the potential influence of opioid analgesics. Objectives:.
Georgia C. Richards, Lesley J. Lluka, Maree T. Smith, Catherine Haslam, Brendan Moore, James O'Callaghan, Jenny Strong   +6 more
doaj   +1 more source

Barriers to the development of palliative care in Western Europe [PDF]

, 2010
The Eurobarometer Survey of the <i>EAPC Task Force on the Development of Palliative Care in Europe</i> is part of a programme of work to produce comprehensive information on the provision of palliative care across Europe.
A. Giordano, Bercovitch M., C. Centeno, Centeno C., Centeno C., Centeno C., D. Clark, F. Guillén, J. Rocafort, K. Hegedus, L. de Lima, Lynch T., M. Filbet, M. Wright, Martin-Moreno J., O. Belle, Polgar S., Recommendation Rec, Rocafort J., Strauss AL, T. Lynch   +20 more
core   +1 more source