Results 21 to 30 of about 120,626 (262)

Narcotic Analgesics: OPIOIDS [PDF]

, 2019
Opioids are morphine-like analgesics used for the management of severe pain, such as acute pain and cancer pain. They are mostly preferred in cases of acute and chronic severe pain.
Erbaba, Hülya
core   +1 more source

Pain medication purchases before and after total hip and knee arthroplasty: a register study of 329,743 arthroplasties

Acta Orthopaedica, 2022
Background and purpose: Total hip (THA) and knee (TKA) arthroplasty are effective pain treatment in osteoarthritis; however, there are patients with long-term pain and in need of analgesics.
Ville Turppo, Reijo Sund, Jukka Huopio, Heikki Kröger, Joonas Sirola   +4 more
doaj   +1 more source

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates

, 2021
Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the effects of systemic opioid analgesics in neonates (term or preterm) undergoing surgery, on mortality, pain and major neurodevelopmental ...
Stempel, Katarzyna S., Borges do Nascimento, Israel Junior, Kinoshita, Mari, Bruschettini, Matteo   +3 more
core   +1 more source

Predictors of shortages of opioid analgesics in the US: Are the characteristics of the drug company the missing puzzle piece?

PLoS ONE, 2021
BackgroundShortages of opioid analgesics are increasingly common, interfere with patient care and increase healthcare cost. This study characterized the incidence of shortages of opioid analgesics in the period 2015-2019 and evaluated potential ...
Rosa Rodriguez-Monguio, Mahim Naveed, Enrique Seoane-Vazquez   +2 more
doaj   +1 more source

Morphine Metabolism in Human Skin Microsomes [PDF]

, 2012
For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin.
Heilmann, S., Küchler, S., Schäfer-Korting, Monika, Küchler, Sarah, Schäfer-Korting, M.   +4 more
core   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Literary investigation on the origin of poppy and other narcotics Research Articles

Journal of Pharmacopuncture, 2009
Objectives : This study was performed to developing orally administered analgesics and locally injected pharmacopuncture analgesics like opioids. Methods : Literary investigation on the origin of poppy (Papaver somniferum L) and other narcotics was ...
Lim Chung San, Han Young ju, Kang Kye Sung, Lee Kwang Ho, Kim Doo Young , Kwon Ki Rok   +5 more
doaj   +1 more source

Journey of Oliceridine: A Novel Opioid

Journal of Marine Medical Society, 2022
Opioid analgesics play a crucial role in the management of acute pain, but its use is often limited by various adverse effects, especially nausea, vomiting, and respiratory depression.
A Tejus, Sharmila Sinha, Prafull Mohan, A G Mathur   +3 more
doaj   +1 more source

Prescription analgesic medication use among osteoarthritis patients

Journal of Orthopaedic Surgery, 2023
Objective Pharmacotherapy is the most common strategies to reduce pain for osteoarthritis (OA) patients. To analyze the trend and pattern of prescription analgesic medication use in American OA patients.
Zhenzhen Huang, Xinxin Chen, Xihong Gan, Jiajia Chen   +3 more
doaj   +1 more source

Type of Opioids Analgesics by Regulation Level.

, 2013
Type of Opioids Analgesics by Regulation Level.
Philip H. Kass (305921), Huijun Han (305918), Barth L. Wilsey (305924), Chin-Shang Li (305925)   +3 more
core   +1 more source