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Optimizing deprescribing of hospital-initiated opioids: a multi-level consensus study bridging evidence, expertise, and patient perspectives. [PDF]
Rainer M +4 more
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Drug Overdose Deaths in the United States, 2023-2024.
Garnett MF, Miniño AM.
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Opioid and non-opioid analgesics
Best Practice & Research Clinical Anaesthesiology, 2003Opioids are the most potent analgesics. Toxicity results either from effects mediated by variation in affinity and intrinsic efficacy at specific opioid receptors or, rarely, from a direct toxic effect of the drugs. For some adverse effects, opioids exhibit a 'dual pharmacology' whereby these effects are usually observed only in pain-free individuals ...
Stephan A, Schug +2 more
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Veterinary Clinics of North America: Small Animal Practice, 2000
Opioids are useful and potent drugs for the management of pain in small animal patients. They have a wide therapeutic index and can be given by a number of different routes. Some of these techniques (e.g., epidural and intraarticular) allow for the production of profound analgesia in a localized area of the body while limiting the dose and the side ...
openaire +2 more sources
Opioids are useful and potent drugs for the management of pain in small animal patients. They have a wide therapeutic index and can be given by a number of different routes. Some of these techniques (e.g., epidural and intraarticular) allow for the production of profound analgesia in a localized area of the body while limiting the dose and the side ...
openaire +2 more sources
British journal of hospital medicine, 1997
This article discusses recent developments in opioid pharmacology. Selective activity at different opioid receptors promises, but has not yet provided, a strong analgesic without opioid side-effects. The startling pharmacokinetic profile of the new esterase-metabolized intravenous opioid, remifentanil, is reflected in the rapid onset of effect and ...
A R, Rushton, J R, Sneyd
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This article discusses recent developments in opioid pharmacology. Selective activity at different opioid receptors promises, but has not yet provided, a strong analgesic without opioid side-effects. The startling pharmacokinetic profile of the new esterase-metabolized intravenous opioid, remifentanil, is reflected in the rapid onset of effect and ...
A R, Rushton, J R, Sneyd
openaire +1 more source

