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The opioid drugs—opium and its derivatives, particularly morphine, heroin, codeine, hydrocodone, and oxycodone—have played a unique and problematic role in the history of medicine: on the one hand, as highly effective analgesics for the relief of severe and chronic pain; on the other, as dangerously addictive substances that have led many individuals ...
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CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016
JAMA - Journal of the American Medical Association, 2016Deborah Dowell, Roger Chou
exaly

