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Veterinary Clinics of North America: Small Animal Practice, 2000
Opioids are useful and potent drugs for the management of pain in small animal patients. They have a wide therapeutic index and can be given by a number of different routes. Some of these techniques (e.g., epidural and intraarticular) allow for the production of profound analgesia in a localized area of the body while limiting the dose and the side ...
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Opioids are useful and potent drugs for the management of pain in small animal patients. They have a wide therapeutic index and can be given by a number of different routes. Some of these techniques (e.g., epidural and intraarticular) allow for the production of profound analgesia in a localized area of the body while limiting the dose and the side ...
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The American Journal of Medicine, 1984
The clinical pharmacology of the narcotic-type analgesics is discussed in depth. Relative analgesic potency, peak and duration of analgesia, oral potency, and adverse effects are reviewed, With an emphasis on the clinical application of this knowledge.
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The clinical pharmacology of the narcotic-type analgesics is discussed in depth. Relative analgesic potency, peak and duration of analgesia, oral potency, and adverse effects are reviewed, With an emphasis on the clinical application of this knowledge.
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On subclasses of opioid analgesics
Current Medical Research and Opinion, 2014The history of discovery of analgesic drugs has followed a trajectory from original serendipitous discovery of plant-derived substances to laboratory creation of customized molecules that are intentionally designed to interact with specific receptors of neurotransmitters involved in either the transmission of the pain signal or the attenuation of such ...
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2023
This chapter starts by desribing morphine extracted from opium and explains why it is known as one of the oldest drugs used in medicine. It considers morphine as a powerful analgesic that has various side effects, the most serious being respiratory depression, tolerance, and dependence. It also analyzes the important binding groups on morphine, such as
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This chapter starts by desribing morphine extracted from opium and explains why it is known as one of the oldest drugs used in medicine. It considers morphine as a powerful analgesic that has various side effects, the most serious being respiratory depression, tolerance, and dependence. It also analyzes the important binding groups on morphine, such as
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2009
Analgesia may be enhanced with non-opioid and opioid analgesics, as well as coanalgesic agents. Non-opioid analgesics and short-acting opioids in chronic pain should be limited to infrequent, intermittent use for severe pain flares. Long-term risk for gastric and renal toxicity with analgesics is minimized with opioid analgesics ...
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Analgesia may be enhanced with non-opioid and opioid analgesics, as well as coanalgesic agents. Non-opioid analgesics and short-acting opioids in chronic pain should be limited to infrequent, intermittent use for severe pain flares. Long-term risk for gastric and renal toxicity with analgesics is minimized with opioid analgesics ...
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The opioid drugs—opium and its derivatives, particularly morphine, heroin, codeine, hydrocodone, and oxycodone—have played a unique and problematic role in the history of medicine: on the one hand, as highly effective analgesics for the relief of severe and chronic pain; on the other, as dangerously addictive substances that have led many individuals ...
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