Results 101 to 110 of about 354,000 (376)

Safety issues of current analgesics: an update

Clujul Medical, 2015
Pain represents a complex experience which can be approached by various medicines. Non-opioid and opioid analgesics are the most common drugs used to manage different types of pain.
I. Cazacu, C. Mogoșan, F. Loghin
semanticscholar   +1 more source

Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications

Advanced Materials, EarlyView.
A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung, Jamal Abu Shihada, Simon Decke, Lina Koschinski, Peter Severin Graff, Sebastián Maruri Pazmino, Anke Höllig, Henner Koch, Simon Musall, Andreas Offenhäusser, Viviana Rincón Montes   +10 more
wiley   +1 more source

Gender differences in dispensed analgesics in Sweden during 2006–2015 – an observational, nationwide, whole-population study

International Journal of Women's Health, 2018
Emmanuel Bäckryd Pain and Rehabilitation Centre, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden Introduction: A potentially illuminating way of looking at gender differences in health and disease is to
Bäckryd E
doaj  

Pharmacogenomics and Opioid Analgesics: Clinical Implications

International Journal of Genomics, 2015
Variation exists in patient response on analgesic treatment in terms of efficacy and safety. This variation may be in part explained by pharmacogenomics.
E. Yiannakopoulou
semanticscholar   +1 more source

Advancements in Biochar as a Sustainable Adsorbent for Water Pollution Mitigation

Advanced Science, EarlyView.
Biochar, obtained through pyrolysis of organic waste, serves as a sustainable solution for wastewater treatment due to its adaptability and low‐cost nature. This review comprehensively examines recent advancements in biochar production, functional modifications, and applications, highlighting the integration of machine learning and artificial ...
Devika Laishram, Su‐Bin Kim, Seul‐Yi Lee, Soo‐Jin Park   +3 more
wiley   +1 more source

Reduction of breast cancer relapses with perioperative non-steroidal anti-inflammatory drugs: new findings and a review [PDF]

arXiv, 2013
To explain a bimodal pattern of hazard of relapse among early stage breast cancer patients identified in multiple databases, we proposed that late relapses result from steady stochastic progressions from single dormant malignant cells to avascular micrometastases and then on to growing deposits.
arxiv  

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Delivery of Human iPSC‐Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells

Advanced Science, EarlyView.
Human induced pluripotent stem cell‐derived retinal pigment epithelial (hiPSC‐RPE) cells, cultured on a clinically relevant PDLLA scaffold, are transplanted into immunosuppressed minipigs. The study demonstrates the viability, integration, and preservation of RPE‐specific features without gliosis or neuroinflammation, supporting their potential as a ...
Anna Macečková Brymová, Francisco Javier Rodriguez‐Jimenez, Annika Konrad, Yaroslav Nemesh, Muhammed Arshad Thottappali, Ana Artero‐Castro, Ruslan Nyshchuk, Anastasiia Kolesnikova, Brigitte Müller, Hana Studenovska, Jana Juhasova, Stefan Juhas, Ivona Valekova, Dunja Lukovic, Claudia Aleman, Taras Ardan, Saskia Drutovič, Jan Motlik, Zdenka Ellederova, Zbinek Straňák, Miroslav Veith, Lyubomyr Lytvynchuk, Ruchi Sharma, Kapil Bharti, Goran Petrovski, Pavla Jendelova, Knut Stieger, Slaven Erceg   +27 more
wiley   +1 more source

Contrast‐enhanced micro‐computed tomography of compartment and time‐dependent changes in femoral cartilage and subchondral plate in a murine model of osteoarthritis

The Anatomical Record, Volume 306, Issue 1, Page 92-109, January 2023., 2023
Abstract A lack of understanding of the mechanisms underlying osteoarthritis (OA) progression limits the development of effective long‐term treatments. Quantitatively tracking spatiotemporal patterns of cartilage and bone degeneration is critical for assessment of more appropriately targeted OA therapies.
Deva D. Chan, Maleeha Mashiatulla, Jun Li, Ryan D. Ross, Meghana Pendyala, Amit Patwa, Mark W. Grinstaff, Anna Plaas, D. Rick Sumner   +8 more
wiley   +1 more source

Functional neuroimaging of psychedelic experience: An overview of psychological and neural effects and their relevance to research on creativity, daydreaming, and dreaming [PDF]

arXiv, 2016
Humans have employed an incredible variety of plant-derived substances over the millennia in order to alter consciousness and perception. Among the innumerable narcotics, analgesics, 'ordeal' drugs, and other psychoactive substances discovered and used in ritualistic contexts by cultures around the world, one class in particular stands out not only for
arxiv