Results 81 to 90 of about 175,254 (314)

Frequent use of over-the-counter analgesics among adolescents – a warning sign of troubled lives [PDF]

open access: yes, 2018
Some adolescents have a high consumption of over-the-counter analgesics. One in ten are daily users, while 25 percent use over-the-counter analgesics weekly.
Skarstein, Siv
core   +1 more source

Do NSAIDs and Other Pain Relief Drugs Can Inhibit the Growth of Lactobacillaceae?

open access: yesPolish Journal of Microbiology, 2023
Non-steroidal anti-inflammatory drugs (NSAIDs) commonly used in clinical practice may cause gastrointestinal injuries and influence the gut microbiota.
Kruszewska Hanna   +2 more
doaj   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

Drugs in pregnancy

open access: yesFogorvosi Szemle, 2019
There are differences between the dental treatments of pregnant and non-pregnant patients. Pregnant women often attend the dentist’s office due to a higher risk of hormone related dental complications, which are induced by pregnancy.
Réka Miklós   +4 more
doaj   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

open access: yesAdvanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang   +12 more
wiley   +1 more source

COMPARISON OF HEMODYNAMIC EFFECTS OF MORPHINE, BUTORPHANOL, BUPRENORPHINE AND PENTAZOCINE ON ICU PATIENTS [PDF]

open access: yes, 1985
Morphine and narcotic agonist-antagonists have been used to assist ICU patients in adapting to mechanical ventilation. In this study, 10 mg of morphine and the equipotent doses of synthetic analgesics, 2 mg of butorphanol, 0.6 mg of buprenorphine or 30 ...
Chieko, MITAKA   +3 more
core   +2 more sources

The Analgesic Antipyretics [PDF]

open access: yesThe American Journal of the Medical Sciences, 1902
n ...
openaire   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

open access: yesAdvanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh   +7 more
wiley   +1 more source

Prescribing of meprobamate-containing combination analgesics in South Africa [PDF]

open access: yes, 2016
Background: Meprobamate is a constituent of various combination analgesics in South Africa. Due to the lack of recent literature on the prescribing patterns of combination analgesics containing meprobamate and in the light of its possible higher re ...
Truter, I., I. Truter, Truter, I
core   +2 more sources

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