Results 81 to 90 of about 41,207 (254)
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
Advanced Science, EarlyView.A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Over-the-counter analgesics require closer monitoring.
, 2010 Physicians should ask their patients specifically about the use of non-prescribed analgesics when taking medication histories, concluded the largest published collection of cases examining over-the-counter (OTC) codeine-ibuprofen misuse.
Gantly, Dara
core
Antipyretic analgesics: basic aspects
, 2006 Antipyretic analgesics are among the most often used medications worldwide. Their major mechanism of action is the blockade of synthesis of prostanoids. These are lipid mediators, which are produced from arachidonic acid in response to tissue damage and ...
Zeilhofer, Hanns Ulrich; https://orcid.org/ +1 more
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Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
, 2014 Analgesics are drugs used to relieve pain. They are divided into groups: opioids, non-steroidals, and adjuvants. This chapter gives you detailed information on their pharmacology.
Anthea Hatfield
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Knowledge of opioid analgesics intensive care
, 2021 Bakalářská práce se zabývám znalostí opioidních analgetik v intenzivní péči. Práce je rozdělena na část teoretickou a výzkumnou. Teoretická část se zaměřuje na opioidní analgetika a jejich možné využití v intenzivní péči, krajově poté bolestí a léčbou ...
Prüherová, Adéla
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Advanced Science, EarlyView.MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang +7 more
wiley +1 more source
International Journal of Women's Health, 2018 Emmanuel Bäckryd Pain and Rehabilitation Centre, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden Introduction: A potentially illuminating way of looking at gender differences in health and disease is to
Bäckryd E
doaj
Journal of Pain Research, 2020 Verónica Varas,1 Paz Bertinelli,1 Pablo Carrasco,1 Nicole Souper,1 Patricio Álvarez,1 Stefan Danilla,2 José Ignacio Egaña,1,3 Antonello Penna,1,4 Sergio Sepúlveda,2 Virginia Arancibia,1 María Gabriela Á ...
Varas V +11 more
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Advanced Science, EarlyView.Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi +7 more
wiley +1 more source