Electroencephalography and analgesics [PDF]
To assess centrally mediated analgesic mechanisms in clinical trials with pain patients, objective standardized methods such as electroencephalography (EEG) has many advantages.
Drewes, Asbjorn Mohr +10 more
core +1 more source
Self-Medication practices with analgesics among medical students [PDF]
Practice of self-medication with analgesics is thought to be rampant among medical students. This study was undertaken to figure out whether there is a difference in usage of analgesics with theoretical background (third year students) to those without ...
Hanumanthu, Lalitha +3 more
core +2 more sources
Association between WHO First-Step Analgesic Use and Risk of Breast Cancer in Women of Working Age
We assessed the association between breast cancer and analgesic use in women of a specific working-age group. The Korean National Health Insurance Service–National Sample Cohort database (KNHIS–NSC) data were analyzed.
Hyun Sook Oh, Hwa Jeong Seo
doaj +1 more source
Structural Guidance in 3D Microgel‐in‐Hydrogel Systems to Improve Chondrogenesis
The Anisogel, an anisotropic microgel‐in‐hydrogel system, guides chondrogenic differentiation of human mesenchymal stromal cells (hMSCs) modulated by the alignment and size of anisometric microgels. Chondrogenic markers are upregulated in an in vitro model and guided tissue infiltration is enhanced in a semi‐orthopedic mouse model due to the physico ...
Julia Kamp +12 more
wiley +1 more source
Preclinical and Clinical Pharmacology of Hydrocodone for Chronic Pain: A Mini Review
Hydrocodone is one of the most prescribed oral analgesic drugs and it is one of the most abused drugs in general population. It is a mu-opioid agonist predominantly metabolized to the O-demethylated product hydromorphone and to the N-demethylated product
Luigi Cardia +7 more
doaj +1 more source
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh +7 more
wiley +1 more source
Risks associated with borrowing and sharing of prescription analgesics among patients observed by pain management physicians in Croatia: a qualitative study [PDF]
Filipa Markotic,1 Livia Puljak2 1Centre for Clinical Pharmacology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina; 2Laboratory for Pain Research, University of Split School of Medicine, Split, Croatia Background: Understanding and ...
Markotic F, Puljak L
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Antipyretic analgesics: basic aspects [PDF]
Antipyretic analgesics are among the most often used medications worldwide. Their major mechanism of action is the blockade of synthesis of prostanoids. These are lipid mediators, which are produced from arachidonic acid in response to tissue damage and ...
Zeilhofer, Hanns Ulrich; https://orcid.org/ +1 more
core +1 more source
Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim +5 more
wiley +1 more source
Regular use of traditional analgesics predicts major coronary events: A cohort study [PDF]
Mikko Haara1, Markku Heliövaara2, Jari PA Arokoski3, Paul Knekt2, Pirjo Manninen4, Arpo Aromaa2, Antti Reunanen2, Olli Impivaara2, Heikki Kröger51Bone and Cartilage Research Unit (BCRU), University of Kuopio, Kuopio, Finland; 2National ...
Paul Knekt +5 more
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