Involvement of Endogenous Opioid System in Swim Stress-Induced Pain Modulation During the Interphase of the Formalin Test [PDF]
Basic and Clinical Neuroscience, 2019 Introduction: Some evidence demonstrates endogenous inhibitory pathways of pain involved in the interphase (phase between early and later phase) of the formalin test.
Ali Reza Moslem +3 more
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Modulation of Different Phases of Formalin Test by Force Swim Stress [PDF]
Basic and Clinical Neuroscience, 2014 Introduction: The formalin test is the most accepted chemical test for evaluation of nociception. It requires the injection of an adequate amount of formalin into the surface of the hindpaw. Formalin test consists of phase 1 (0-7 min) and phase 2 (15-60)
Mohammad Mohammad-Zadeh +3 more
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Formalin Itch Test: Low-Dose Formalin Induces Histamine-Independent, TRPA1-Mediated Itch in Mice [PDF]
Frontiers in Medicine, 2021 Chronic itch is a common distressing symptom of many diseases, which reduced patient's quality of life. The mechanistic study on itch and screening for new anti-itch drugs require the development of new pre-clinical itch animal models.
Xu Liu +10 more
doaj +3 more sources
Mechanism of Antinociceptive Effect of Vanillin in Formalin Test [PDF]
International Journal of Preventive MedicineBackgrounds: Vanillin is the active component of Vanillus planifolia seeds and is widely used as a flavoring agent in food and pharmaceutical industries. It has shown anti-inflammatory and antinociceptive properties.
Valiollah Hajhashemi +2 more
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Differential Antinociceptive Efficacy of Peel Extracts and Lyophilized Juices of Three Varieties of Mexican Pomegranate (Punica granatum L.) in the Formalin Test [PDF]
Plants, 2022 Pharmacological treatment of pain often causes undesirable effects, so it is necessary to look for natural, safe, and effective alternatives to alleviate painful behavior.
José Antonio Guerrero-Solano +8 more
doaj +2 more sources
A refinement to the formalin test in mice. [PDF]
F1000Res, 2019 The constant refinement of tests used in animal research is crucial for the scientific community. This is particularly true for the field of pain research, where ethical standards are notably sensitive. The formalin test is widely used in pain research and some of its mechanisms resemble those underlying clinical pain in humans.
Lopes DM +4 more
europepmc +6 more sources
Spinal gabapentin is antinociceptive in the rat formalin test
Neuroscience Letters, 1997 Gabapentin is a novel anticonvulsant that may be of value for the relief of clinical pain. To determine whether gabapentin is antinociceptive after spinal administration, the drug was given via an intrathecal catheter in doses from 6 to 200 micrograms/rat 10 min prior to intraplantar formalin.
Naohito Shimoyama +4 more
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HA- and HI-Test for Myxoviruses with Formalinized Erythrocytes
Nippon Saikingaku Zasshi, 1967 With formalinized erythrocytes (FRC) from chickens, men and guinea-pigs, hemagglutination and hemagglutination-inhibition test for myxoviruses with Salk pattern method were studied and the results obtained are as follows.1) Spontaneous agglutination of FRC was prevented with 0.05 per cent bovine serum albumin in the suspending medium.2) There was no or
Yukio Yamazi +4 more
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Effects of Intraplantar Morphine in the Mouse Formalin Test
Japanese Journal of Pharmacology, 2000 We studied the effects of intraplantar morphine in the formalin test in mice. Intraplantarly administered morphine (30 - 300 microg) induced analgesic effects at lower doses than intraperitoneally administered morphine. Following the administration of [3H]morphine, the % of radioactivity present in brain was the same by either route.
Ana Baamonde +3 more
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Antinociceptive Effect of Some Biuret Derivatives on Formalin Test in Mice [PDF]
Advanced Pharmaceutical Bulletin, 2014 Purpose: The current study was designed to investigate the antinociceptive effects of several biuret derivatives with N, N`-diphenyl, N-phenyl-N`-alkylphenyl, N,N`-bis alkylphenyl, 2-methylquinoline-4-yl, benzo[d]thiazol-2-ylthio and (1-phenyl-1H ...
Neda Adibpour +3 more
doaj +2 more sources