Results 121 to 130 of about 283,091 (360)
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao +6 more
wiley +1 more source
The specific features of pain syndrome in patients with hemophilia [PDF]
Терапевтический архив, 2016 Aim. To study the nature of pain in hemophilic arthropathy and its prevention ways used by patients with hemophilia. Subjects and methods. A prospective, multicenter, cross-sectional study was conducted to interview 136 patients with hemophilia A or B ...
O K Levchenko +3 more
doaj
ANALGESIC ACTIVITY OF DIPIPANONE HYDROCHLORIDE IN STUDENT VOLUNTEERS [PDF]
, 1957 D. A. Cahal
openalex +1 more source
Advanced Materials Technologies, EarlyView.Thermal annealing improves the structure, stiffness, and piezoelectric properties of poly(vinylidene flouride‐trifluoroethylene) (PVDF‐TrFE) nanofiber scaffolds. These annealed scaffolds promote Schwann cell proliferation and matrix remodeling in vitro and demonstrate in vivo biocompatibility.
Maksym Krutko +12 more
wiley +1 more source
Advanced Synthesis &Catalysis, EarlyView.Through the exploiting of visible‐light, a key photoactive complex, and an acid‐catalyzed proton‐coupled electron transfer, polycyclic sulfonylated benzimidazoles are obtained through a domino process including sulfonylation, C–H activation, and annulation. Diarylmethylium tetrafluoroborates are employed as inexpensive organocatalyst capable of forming
Polyssena Renzi +4 more
wiley +1 more source
Photoredox‐Catalyzed Synthesis of a Novel Class of Fluoroalkyl Pyrazolones
Advanced Synthesis &Catalysis, EarlyView.A photoredox strategy enables regioselective synthesis of fluoroalkyl 2‐pyrazolin‐5‐ones via radical addition and cyclization. This mild, metal‐free method shows a broad substrate scope, operates in batch and flow systems, and offers a sustainable approach to fluorinated heterocycles with potential applications in medicinal chemistry.
Emanuele F. Pissinati +3 more
wiley +1 more source
Comparison of opioid prescribing by dentists in the United States and England [PDF]
, 2019 Importance: The United States consumes most of the opioids worldwide despite representing a small portion of the world\u27s population. Dentists are one of the most frequent US prescribers of opioids despite data suggesting that nonopioid analgesics are ...
Calip, Gregory S +7 more
core +1 more source
The Management of Pain, with Special Emphasis on the Use of Analgesic Block in Diagnosis, Prognosis and Therapy [PDF]
, 1954 FRANCE ALEXANDER
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Advanced Synthesis &Catalysis, EarlyView.A stereoselective one‐step (3 + 3)‐cycloaddition between in situ generated pyrrole‐3‐methides and carbonyl ylides has been developed using cooperative rhodium and chiral phosphoric acid catalysis. The reaction affords oxa‐bridged cyclohepta[1,2‐b]pyrroles bearing three stereogenic centers, including two quaternary ones, in high yields and ...
Philipp Stehr, Christoph Schneider
wiley +1 more source
HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in bunionectomy: phase III results from the randomized EPOCH 1 study. [PDF]
, 2019 BACKGROUND AND OBJECTIVES: There is a need for local anesthetics that provide consistent analgesia through 72 hours after surgery. This study evaluates the use of HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release,
Gimbel, Joseph S. +4 more
core +1 more source