Analgesics for Dental Implants: A Systematic Review
Frontiers in Pharmacology, 2021 Postsurgical pain is commonly associated with dental and oral surgery, and the use of analgesics has been investigated in the management of postoperative pain.
Matteo Melini +4 more
doaj +1 more source
Addressing the Global Tragedy of Needless Pain: Rethinking the United Nations Single Convention on Narcotic Drugs [PDF]
, 2007 The lack of medical availability of effective pain medication is an enduring and expanding global health calamity. Despite important medical advances, pain remains severely under-treated worldwide, particularly in developing countries.
Allyn L. Taylor +11 more
core +2 more sources
Synthetic route towards potential bivalent ligands possessing opioid and D2/D3 pharmacophores [PDF]
Journal of the Serbian Chemical Society, 2019 A scalable, cost-efficient and simple synthetic pathway towards potential bivalent opioid/dopamine receptor ligands was developed and optimized. Three novel compounds that contain both opioid and dopamine pharmacophores linked by the four methylene group
Jevtić Ivana I. +3 more
doaj +1 more source
The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods [PDF]
, 1964 1. The forms of irritation causing inflammation and pain are reviewed, with reference to the significance of histamine, serotonin and bradykinin and in particular to the interrelationship between inflammation and pain. 2.
Wilhelmi, G.
core +1 more source
PharmaceuticalsTramadol, a weak μ-opioid receptor agonist, has been used worldwide for pain management. It is considered to have a favorable safety profile without serious adverse events; however, safety issues of respiratory depression were proposed by regulatory ...
Sunny Park +5 more
doaj +1 more source
Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review [PDF]
Iranian Journal of Basic Medical SciencesJuglans regia L. (walnut) has a rich history in traditional medicine due to its various medicinal properties, including its neuroprotective effects on nervous system disorders.
Mahboobeh Ghasemzadeh Rahbardar +1 more
doaj +1 more source
Toward personalized medicine for pharmacological interventions in neonates using vital signs
Paediatric & Neonatal Pain, 2021 Vital signs, such as heart rate and oxygen saturation, are continuously monitored for infants in neonatal care units. Pharmacological interventions can alter an infant's vital signs, either as an intended effect or as a side effect, and consequently ...
Caroline Hartley
doaj +1 more source
Frontiers in Pharmacology, 2022 Background: Given the limitations of three-step analgesic therapy and the extensive use of traditional Chinese medicine injections (TCMIs) for cancer-related pain (CRP), this network meta-analysis (NMA) aims to compare the efficacy and safety of ...
Pengli Su +5 more
doaj +1 more source
In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]
, 2018 Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta +4 more
core +2 more sources
Update on medication-overuse headache and its treatment [PDF]
, 2015 OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA +2 more
core +1 more source