Toward personalized medicine for pharmacological interventions in neonates using vital signs
Paediatric & Neonatal Pain, 2021 Vital signs, such as heart rate and oxygen saturation, are continuously monitored for infants in neonatal care units. Pharmacological interventions can alter an infant's vital signs, either as an intended effect or as a side effect, and consequently ...
Caroline Hartley
doaj +1 more source
Frontiers in Pharmacology, 2022 Background: Given the limitations of three-step analgesic therapy and the extensive use of traditional Chinese medicine injections (TCMIs) for cancer-related pain (CRP), this network meta-analysis (NMA) aims to compare the efficacy and safety of ...
Pengli Su +5 more
doaj +1 more source
In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]
, 2018 Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta +4 more
core +2 more sources
PharmaceuticalsTramadol, a weak μ-opioid receptor agonist, has been used worldwide for pain management. It is considered to have a favorable safety profile without serious adverse events; however, safety issues of respiratory depression were proposed by regulatory ...
Sunny Park +5 more
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Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review [PDF]
Iranian Journal of Basic Medical SciencesJuglans regia L. (walnut) has a rich history in traditional medicine due to its various medicinal properties, including its neuroprotective effects on nervous system disorders.
Mahboobeh Ghasemzadeh Rahbardar +1 more
doaj +1 more source
Tapentadol extended release for the management of chronic neck pain [PDF]
, 2017 BACKGROUND: The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER).
Coluzzi, Flaminia
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Use of Opioids and Other Analgesics Before and After Primary Surgery for Adult Spinal Deformity: A 10-Year Nationwide Study [PDF]
Neurospine, 2020 Objective To report the 1-year pre and postoperative analgesic use in patients undergoing primary surgery for adult spinal deformity (ASD) and assess risk factors for chronic postoperative opioid use.
Frederik Taylor Pitter +5 more
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Medication use by early-stage breast cancer survivors: a 1-year longitudinal study. [PDF]
, 2016 PurposeThe aim of this study is to characterize the patterns of medication use by early-stage breast cancer (ESBC) survivors from diagnosis to 1 year post-chemotherapy.MethodsA single-center longitudinal study was conducted with ESBC patients diagnosed ...
Chan, Alexandre +4 more
core +1 more source
Update on medication-overuse headache and its treatment [PDF]
, 2015 OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA +2 more
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Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Annals of Clinical and Translational Neurology, EarlyView.Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski +13 more
wiley +1 more source