Results 41 to 50 of about 117,427,695 (333)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

System oriented delta sigma analog-to-digital modulator design for ultra high precisoin data acquisition applications [PDF]

open access: yes, 2008
textAs high precision data acquisition systems continue to improve their performance and power efficiency to migrate into portable devices, increasing demands are placed on the performance and power efficiency of the analog-to-digital conversion ...
Yang, Yuqing, Ph. D.
core  

Rancang Bangun ECG Simulator Menggunakan Digital to Analog Converter R-2R

open access: yesJurnal Teknologi Informatika & Komputer, 2021
Abstrak Pengujian atau mengkalibrasi alat Electro CardioGraph membutuhkan alat ECG simulator / phantom. Saat melakukan penelitian terdahulu, peneliti sangat tergantung dengan komponen DAC impor.
Mulyatno Saimi
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Dickson-Charge-Pump-Based Voltage-to-Time Conversion for Time-Based ADCs in 28-nm CMOS

open access: yesIEEE Open Journal of Circuits and Systems, 2021
This article demonstrates a digitally friendly time-based analog-to-digital converter (ADC) exploiting Dickson charge-pump (CP) as part of a voltage-to-time conversion (VTC) implemented in 28-nm CMOS. In the proposed technique, the Dickson CP generates a
Ali Esmailiyan   +4 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Analog to Digital Converter-Patent [PDF]

open access: yes, 1966
Analog to digital converter for converting pulses to ...
Doong, H.
core  

Analog-to-Digital Converter Comprising Selective Comparators

open access: yes
An analog-to-digital converter comprises a plurality of comparators 30, one input of each comparator being connected to an analog signal input 24, and the other input of each comparator being connected so as to receive a respective portion of a reference
Bremner, Duncan
core   +5 more sources

A low-power reconfigurable analog-to-digital converter

open access: yes2001 IEEE International Solid-State Circuits Conference. Digest of Technical Papers. ISSCC (Cat. No.01CH37177), 2001
A reconfigurable analog-to-digital converter digitizes signals over a 1 Hz-10 MHz bandwidth and 6 to 16 b resolution with adaptive power consumption. The converter achieves this by reconfiguring between pipeline and /spl Delta//spl Sigma/ architectures ...
K. Gulati, Hae-Seung Lee
semanticscholar   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

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