Results 31 to 40 of about 27,607 (262)

An Approach to Determine Noise Model Parameter for Submicron MOSFET from RF Noise Figure Measurement

IEEE Journal of the Electron Devices Society
An extraction method to obtain the noise model parameter $T_{\mathrm { d}}$ in deep submicron MOSFETs directly from radio frequency (RF) scattering parameters and noise figure measurements is presented. A simplified noise equivalent circuit, along with
Hanqi Gao, Jing Jin, Jianjun Zhou
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

All‐Optic Logical Operations Based on the Visible‐Near Infrared Bipolar Optical Response

Advanced Science
The burgeoning need for extensive data processing has sparked enthusiasm for the development of a novel optical logic gate platform. In this study, junction field‐effect phototransistors based on molybdenum disulfide/Germanium (MoS2/Ge) heterojunctions ...
Jie You, Zhao Han, Ningning Zhang, Qiancui Zhang, Yichi Zhang, Yang Liu, Yang Li, Jinping Ao, Zuimin Jiang, Zhenyang Zhong, Hui Guo, Huiyong Hu, Liming Wang, Zhangming Zhu   +13 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Low Turn-Off Loss 4H-SiC Insulated Gate Bipolar Transistor With a Trench Heterojunction Collector

IEEE Journal of the Electron Devices Society, 2020
In this work, an improved 4H-SiC insulated gate bipolar transistor (IGBT), or CTH-IGBT, with a trench p-polySi/p-SiC heterojunction on the backside of the device is proposed to reduce the turn-off energy loss (Eoff) and turn-off time (Toff).
Ying Wang, Cheng-Hao Yu, Hong-Kai Mao, Xue Wu, Fang-Wen Su, Xing-Ji Li, Jian-Qun Yang   +6 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A Novel Super Transistor-Based High-Performance CCII and Its Applications

Elektronika ir Elektrotechnika, 2018
In this paper a high-performance low-voltage low-power CMOS second-generation current conveyor (CCII) is presented. The proposed CCII is based on super transistor (ST) and enables low input impedance at X terminal and high output impedance at Z terminal.
Leila Safari, Shahram Minaei
doaj   +1 more source

The Case for Analog Circuit Verification

Electronic Notes in Theoretical Computer Science, 2006
The traditional approach to validate analog circuits is to utilize extensive SPICE-level simulations. The main challenge of this approach is knowing when all important corner cases have been simulated. A new alternative is to utilize formal verification techniques.
Chris J. Myers, Reid R. Harrison, David Walter, Nicholas Seegmiller, Scott Little   +4 more
openaire   +1 more source