Results 51 to 60 of about 886,439 (248)
A single shot coherent Ising machine based on a network of injection-locked multicore fiber lasers
Nature Communications, 2019 For specific computation problems where electronic digital processors have shortcomings in simulating, an analog optical system may be a solution, Here, the authors present an analog all-optical implementation of a coherent Ising machine based on a ...
Masoud Babaeian +8 more
doaj +1 more source
Journal of Low Power Electronics and Applications, 2019 This discussion develops a theoretical analog architecture framework similar to the well developed digital architecture theory. Designing analog systems, whether small or large scale, must optimize their architectures for energy consumption.
Jennifer Hasler
doaj +1 more source
A mixed-signal oscillatory neural network for scalable analog computations in phase domain
Neuromorphic Computing and Engineering, 2023 Digital electronics based on von Neumann’s architecture is reaching its limits to solve large-scale problems essentially due to the memory fetching.
Corentin Delacour +6 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2012 Fractional power computation of matrix is represented. Numerical calculations for ordinary differential equation and its fraction analog is done. Results are compared with Grunvald – Letnikov operator.
Ilyin, I.A. +2 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
On the Effect of Analog Noise in Discrete-Time Analog Computations
, 1998 We introduce a model for analog computation with discrete time in the presence of analog noise that is flexible enough to cover the most important concrete cases, such as noisy analog neural nets and networks of spiking neurons.
Maass, Wolfgang +3 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Noise-Robust conceptors for physical reservoir computing: adaptation to perturbations
Neuromorphic Computing and EngineeringConceptors are a powerful extension of reservoir computing (RC) that enable the selective recall and stabilization of internal dynamics. However, their application to physical RC remains challenging because measured reservoir states are inevitably ...
Gemma Infantes-Llinares +2 more
doaj +1 more source