Results 31 to 40 of about 3,089,886 (293)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

An Improved 4H-SiC Trench MOS Barrier Schottky Diode With Lower On-Resistance

IEEE Access, 2019
An improved 4H-SiC trench MOS barrier Schottky (TMBS) structure that can significantly reduce the specific on-resistance ( $R_{on,sp}$ ) is proposed in this paper.
Fei Cao, Meng-tian Bao, Xue Wu, Wen-Ju Wang, Cheng-Hao Yu, Ying Wang   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Automated Observability Investigation of Analog Electronic Circuits using SPICE [PDF]

, 2011
In the present paper, a computer-aided approach to fault observability investigation of linear analog circuits is developed. The method is based on sensitivity investigation of the test characteristics in the frequency domain.
Atanasov, Anton, Gadjeva, Elissaveta, Shikalanov, Dimitar   +2 more
core  

An Approach to Determine Noise Model Parameter for Submicron MOSFET from RF Noise Figure Measurement

IEEE Journal of the Electron Devices Society
An extraction method to obtain the noise model parameter $T_{\mathrm { d}}$ in deep submicron MOSFETs directly from radio frequency (RF) scattering parameters and noise figure measurements is presented. A simplified noise equivalent circuit, along with
Hanqi Gao, Jing Jin, Jianjun Zhou
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An asynchronous spike event coding scheme for programmable analog arrays [PDF]

, 2008
This paper presents a spike event coding scheme for the communication of analog signals in programmable analog arrays. In the scheme presented here no events are transmitted when the signals are constant leading to low power dissipation and traffic ...
Thomas Jacob Koickal, Koickal, T., Gouveia, L.C., Alister Hamilton, Luiz Carlos Gouveia, Hamilton, A.   +5 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Generation and Verification of Tests for Analog Circuits Subject to Process Parameter Deviations

, 2004
The paper presents a test stimulus generation and fault simulation methodology for the detection of catastrophic faults in analog circuits. The test methodology chosen for evaluation is RMS AC supply current monitoring.
Chalk, CD, Zwolinski, M, Spinks, SJ, Bell, IM   +3 more
core   +1 more source

All‐Optic Logical Operations Based on the Visible‐Near Infrared Bipolar Optical Response

Advanced Science
The burgeoning need for extensive data processing has sparked enthusiasm for the development of a novel optical logic gate platform. In this study, junction field‐effect phototransistors based on molybdenum disulfide/Germanium (MoS2/Ge) heterojunctions ...
Jie You, Zhao Han, Ningning Zhang, Qiancui Zhang, Yichi Zhang, Yang Liu, Yang Li, Jinping Ao, Zuimin Jiang, Zhenyang Zhong, Hui Guo, Huiyong Hu, Liming Wang, Zhangming Zhu   +13 more
doaj   +1 more source