Results 121 to 130 of about 326,210 (336)

Real-time gap-free dynamic waveform spectral analysis with nanosecond resolutions through analog signal processing. [PDF]

Nat Commun, 2020
Konatham SR, Maram R, Romero Cortés L, Chang JH, Rusch L, LaRochelle S, Guillet de Chatellus H, Azaña J.   +7 more
europepmc   +1 more source

The Curcumin Analog (PAC) Has Anti-Oral Cancer Properties Through Impairing Pro-Survival Signaling Pathways and Activating the Cell Death Processes Apoptosis and Autophagy [PDF]

, 2020
Abdelhabib Semlali, Camille Contant, Basem Al‐Otaibi, Ibrahim Al‐Jammaz, Fatiha Chandad   +4 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

EQUIPMENTS TO SINGLE PHOTON REGISTRATION. Part 2. SILICON PHOTOMULTIPLIER SIGNAL PRELIMINARY PROCESSING. (Review)

Приборы и методы измерений, 2015
Bias circuits, output signals and readout electronics of silicon photomultipliers are considered. Requirements to analog IC for SiPM signal preliminary processing are formulated.
O. V. Dvornikov, V. A. Tchekhovski, V. L. Diatlov   +2 more
doaj  

A New Analog Filter for Piezoelectric Sensors Signal Processing Designed for High Speed Weigh in Motion System [PDF]

, 2021
Lhoussaine Oubrich, Mohammed Ouassaid, Mohamed Maâroufi   +2 more
openalex   +1 more source

Reconsidering Linear Transmit Signal Processing in 1-Bit Quantized Multi-User MISO Systems

, 2018
In this contribution, we investigate a coarsely quantized Multi-User (MU)-Multiple Input Single Output (MISO) downlink communication system, where we assume 1-Bit Digital-to-Analog Converters (DACs) at the Base Station (BS) antennas.
De Candido, Oliver, Jedda, Hela, Mezghani, Amine, Nossek, Josef A., Swindlehurst, A. Lee   +4 more
core