Results 131 to 140 of about 4,799,373 (254)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Low voltage high performance CCII for analog signal processing applications
, 2006 Purpose - To provide new structures and applications of CCII for analog signal processing. Design/methodology/approach - New structure and new applications suitable for low voltage analog signal processing. Findings - These structures developed for
Jamuar, S. S., Rajput, S. S.
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Field–programmable analog arrays enable analog signal processing education
, 2005 –In a laboratory environment, the practicality and scope of experiments is constrained by time and financial resources. In the digital hardware design arena, the development of programmable logic devices, such as field–programmable gate arrays (FPGAs ...
Hasler, P +4 more
core
Приборы и методы измерений, 2015 Bias circuits, output signals and readout electronics of silicon photomultipliers are considered. Requirements to analog IC for SiPM signal preliminary processing are formulated.
O. V. Dvornikov +2 more
doaj
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Integrated Circuits for Quantized Analog Signal Processing
, 2018 This thesis presents the new concept of Quantized Analog Signal Processing, which is a method to expand the dynamic range of an analog system by using multiple units covering different portions of the rail-to-rail input range.
Musayev, Javid
core
Nonuniformly coupled microstrip transversal filters for analog signal processing
An analog signal processing technique allowing arbitrary step response is presented. A transversal structure is used with nonuniform contradirectional coupling to provide continuous tapping.
Hayden, Leonard.
core +5 more sources
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source