Results 121 to 130 of about 4,799,373 (254)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The Signal Processing Information Base

open access: yes, 2003
Conference PaperThe SPIB (Signal Processing Information Base) project at Rice University is discussed. This information base will provide the signal processing researcher and the applications engineer with data, programs, and papers that can be accessed ...
Johnson, Don, Shami, P N
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

RF and digital signal processing for software-defined radio: a multi-standard multi-mode approach

open access: yes, 2009
Software-defined radio (SDR) is the hottest area of RF/wireless design, and this title describes SDR concepts, theory, and design principles from the perspective of the signal processing (both on transmission and reception) performed by a SDR system ...
Rouphael, Tony J, Rouphael, Tony J.
core  

Multiple-Access Techniques for Communication Satellites - Analog Modulation, Frequency- Division Multiplexing, and Related Signal Processing Methods [PDF]

open access: yes, 1966
Analog modulation, frequency-division multiplexing and signal processing for multiple-access satellite ...
Reinhart, E. E.
core  

Unbiased Injection of Signal-Dependent Noise in Variance-Stabilized Range

open access: yes, 2016
<p>The design, optimization, and validation of many image processing or image-based analysis systems often requires testing of the system performance over a dataset of images corrupted by noise at different signal-to-noise ratio regimes.
Vieira, Marcelo   +2 more
core   +1 more source

Multifunctional mixed analog/digital signal processor based on integrated photonics

open access: yesOpto-Electronic Science
Photonic signal processing offers a versatile and promising toolkit for contemporary scenarios ranging from digital optical communication to analog microwave operation.
Yichen Wu   +11 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Operating-point driven formulation for analog computer-aided design [PDF]

open access: yes, 2013
In designing analog integrated circuits, the step of selecting device sizes and biases is crucial to enhance the final performance, power, and yield of the circuits.
ESTEBAN TLELO CUAUTLE
core  

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