Results 21 to 30 of about 149,437 (268)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Feeling Like a Bat: A Critique of Thomas Nagel
According to Thomas Nagel’s thought, human beings are incapable of subjectively experiencing what a bat experiences. The only possibilities outlined by the philosopher are: (1) the objective analysis of ethological expressions, that is, the description ...
Roberto Marchesini
doaj +1 more source
ENGELSK SUMMARY: The sculptures on the altarpiece of Aarhus Cathedral are a good example of 'analogism', an understanding of reality (an 'ontology') that presents an ideal reality as a harmonious order.
Hans J. Lundager Jensen
doaj +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Helgener over det hele: Polymorf middelalderkristendom i Vor Frue Kirke, Skive
English ABSTRACT: Drawing on iconographic material in the form of a decoration of church frescoes from the year 1522 in the medieval parish church Vor Frue Kirke in Skive (in Jutland) this article examines the Christian cult and mythology of saints in ...
Nikolaj Skou Haritopoulos
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Descola describes western culture, influenced by the Christian worldview, as “naturalist”. However, semiotic and ethnographic research shows that different perspectives about the relationship between humans and animals coexist with mainstream naturalism.
Jenny Ponzo, Francesco Galofaro
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

