Results 51 to 60 of about 88,613 (352)

Oscillation-based Test Method for Continuous-time OTA-C Filters [PDF]

open access: yes, 2006
“This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders.
Hasan, M., Sun, Y.
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

A mixed-signal implementation of a polychronous spiking neural network with delay adaptation

open access: yesFrontiers in Neuroscience, 2014
We present a mixed-signal implementation of a re-configurable polychronous spiking neural network capable of storing and recalling spatio-temporal patterns. The proposed neural network contains one neuron array and one axon array.
Runchun Mark Wang   +3 more
doaj   +1 more source

High-speed nonlinear focus-induced photoresponse in amorphous silicon photodetectors for ultrasensitive 3D imaging applications

open access: yesScientific Reports, 2022
A large and growing number of applications benefit from simple, fast and highly sensitive 3D imaging sensors. The Focus-Induced Photoresponse (FIP) can achieve 3D sensing functionalities by simply evaluating the irradiance dependent nonlinear sensor ...
Andreas Bablich   +7 more
doaj   +1 more source

Design Of A Current Conveyor Analogue Multiplier For Energy Meter Using 0.35 Μm Mimos Cmos Technology [PDF]

open access: yes, 2007
Analogue VLSI circuits are essential in many real-time signal processing applications as naturally occurring signals are analogue. The four-quadrant analogue multiplier is a key building block in analogue signal processing circuits.
Ng, Min Shen
core  

Block-level bayesian diagnosis of analogue electronic circuits [PDF]

open access: yes2010 Design, Automation & Test in Europe Conference & Exhibition (DATE 2010), 2010
Daily experience with product designers, test and diagnosis engineers it is realized that the depth of interaction among them, ought to be high for successful diagnosis of analogue circuits. With this knowledge in mind, a responsibility was undertaken to choose a popular diagnostic method and define a systematic procedure that binds together the ...
Krishnan, S.   +3 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Semi-inverted linear spaces and an analogue of the broken circuit complex [PDF]

open access: yes, 2019
The image of a linear space under inversion of some coordinates is an affine variety whose structure is governed by an underlying hyperplane arrangement.
Scholten, Georgy, Vinzant, Cynthia
core   +3 more sources

Image interpolation by analogue circuit

open access: yesElectronics Letters, 1992
An analogue computation circuit is proposed for image interpolation. This circuit is designed to maximise the smoothness of the interpolated data. With this circuit, high speed interpolation can be easily achieved.
H.-C. Hsieh, W.-T. Chang
openaire   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez   +12 more
wiley   +1 more source

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