Results 71 to 80 of about 20,345 (263)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Geofluids, 2018 We derive the discrete fracture network (DFN) of a Lower Cretaceous carbonate platform succession exposed at Mt. Faito (Southern Apennines), which represents a good outcrop analogue of the coeval productive units of the buried Apulian Platform in the ...
L. Massaro +6 more
doaj +1 more source
Strike-slip kinematics from crustal to outcrop-scale: the impact of material properties on analogue modelling [PDF]
Solid EarthStrike-slip fault zones commonly display complex kinematics and 3D geometries, with high structural variability along strike and with depth. In this regard, analogue modelling techniques are a powerful tool for investigating such complex structural ...
L. Massaro +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Internet Archaeology, 2017 In the 1980s archaeologists embraced the rapidly expanding field of computer modelling and visualisation as a vehicle for data exploration. Against this backdrop 'virtual archaeology' was conceived.
Gareth Beale, Paul Reilly
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The analogue modeling of boudins
, 2011 Boudins are geologic structures, formed by the extension of a brittle layer, which is sandwiched between two ductile layers. In this work, experiments with non-scaled analogue models were made to investigate the parameters that control the evolution of boudin blocks.
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Analogue Model for the Gravity Sliding of Sediments
Journal of Geoscience Education, 2006 The gravity-driven sliding of soft sediments is modeled using a simple and reusable experiment. Sand, mud and water are shaken in a sealed plastic bottle. When the sand has partially settled, the bottle is tilted by several degrees and left on a stable surface for several hours, until a layer of mud is deposited above the gently dipping sand surface ...
openaire +2 more sources