Results 51 to 60 of about 1,293,993 (389)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Popper's Darwinian analogy [PDF]

open access: yes, 2011
One of the most deeply entrenched ideas in Popper's philosophy is the analogy between the growth of scientific knowledge and the Darwinian mechanism of natural selection. Popper gave his first exposition of these ideas very early on.
Nanay, Bence
core  

Ethnoarchaelogy – the Present as Key to the Past

open access: yesEtnoantropološki Problemi, 2006
  This text discusses the theoretical aspects of ethnoarchaeology, as a discipline that represents a specific hybrid of ethnology and archaeology and thus asserts itself as a significant pathway to building middle-range theories.
Marko Porčić
doaj   +1 more source

An electrical analogy to Mie scattering

open access: yesNature Communications, 2016
Mie scattering is an optical phenomenon that appears when electromagnetic waves, in particular light, are elastically scattered at a spherical or cylindrical object.
J. Caridad   +4 more
semanticscholar   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Analogies in science education: contributions and challenges [PDF]

open access: yesInvestigações em Ensino de Ciências, 2005
An analogy is a comparison between domains of knowledge that have similarities at the levels of characteristics and relationships. Several authors highlight the importance of this tool in the teaching and learning of difficult scientific concepts ...
Maria da Conceição Duarte
doaj  

Modeling Mystery

open access: yesScientia et Fides, 2016
The practice of model-building is very common in analytic philosophical theology. Yet many other theologians worry that any attempt to model God must be hubristic and idolatrous.
William Wood
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Understanding analogical reasoning : viewpoints from psychology and related disciplines [PDF]

open access: yes, 1986
Analogy and metaphor have a long history of study in linguistics, education, philosophy and psychology. Consensus over what analogy is or how analogy functions in language and thought, however, has been elusive. This paper, the first in a two part series,
Hall, Rogers P.
core   +1 more source

Reanalysis of Passive and Negative Prefixes in Seri

open access: yesLinguistic Discovery, 2002
Two productive Seri prefixes, negative and passive, are in a limited number of cases reanalyzed as part of the verb stem. This reanalysis has produced homophonous verb forms: one group is clearly analytical (affix + root) and one group is clearly ...
Stephen A. Marlett
doaj   +1 more source

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