Results 111 to 120 of about 110,798 (311)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Analysis and Criticism of the Comparative Historical Method

, 2021
Teyfur Erdoğdu
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Towards a Discourse for Criticism in Language Teaching: Analysis of Sociocultural Representations in Mass Media [PDF]

, 2010
Vargas Torres, Margarita Rosa
openalex  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

HERMENEUTIKA OTENTISITAS HADIS M. MUSTOFA AZAMI

Farabi, 2017
This article discusses Azami criticism to Ignaz Gholziher and Joseph Schacht. The author tries to integrate the relations of hermeneutics as a solution to solve the issues of  Hadith authenticity, and its interconnected to psychology, that Azami position
Lilik Faiqoh
doaj  

Analysis Of Umit Unal's Film “Nar” By Mise En Scene Criticism Method Ümit Ünal’ın “Nar” Filminin Mizansen Eleştiri Yöntemiyle Analizi

, 2017
Gözde SUNAL
openalex   +1 more source

CRITICISMS OF THE ADVANCED SOLUTIONS OF THE CIVIL CODE REGARDING THE REPAIR OF MORAL DAMAGES TEXT ANALYSIS

, 2023
Sache Neculaescu, Sache Neculaescu
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Annlise Comparativa Dos Mecanismos De Extensso Da Patente De FFrmacos: Uma Crrtica Ao Sistema Brasileiro (Comparative Analysis of the Extension Mechanisms of Medicine Patent: A Criticism of the Brazilian System)

, 2017
Fabrício de Souza Oliveira
openalex   +1 more source