Results 51 to 60 of about 482,820 (312)

Multi-material topology optimization of structural load-bearing capacity using limit analysis

Journal of Theoretical, Computational and Applied Mechanics
We extend the problem of finding an optimal structure with maximum load-bearing capacity to the case of multiple materials. We first consider a reinforcement optimization case where the structure consists of a fixed background matrix material with given strength properties and optimize the reinforcement topology within this material. We discuss the use
Mourad, Leyla, Bleyer, Jeremy, Mesnil, Romain, Nseir, Joanna, Sab, Karam, Raphael, Wassim   +5 more
openaire   +1 more source

A Review on design and analysis of steel bridge with identification of load bearing capacity

International Journal of Advanced Engineering Research and Science, 2023
Strengthening old bridges is an increasingly relevant strategy for risk prevention and operation continuity in management of infrastructures. Transportation networks are subjected to progressively stricter environmental and load conditions, leading to a growing number of deficient structures, also due to aging and deterioration.
Mohini Dharwe, Mohit Kumar Prajapati
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Perbandingan Kapasitas Dukung Aksial Pondasi Tiang Tunggal dengan Beberapa Metode Analisis (Studi Kasus : Pondasi Rumah Sakit Pendidikan Universitas Riau Pekanbaru) [PDF]

, 2014
A pile foundation design should be done carefully and as carefully as possible. Each foundation must be able to support loads up to the limit safely, including supporting the maximum load that may occur.
Muhardi, M. (Muhardi), Sanjaya, G. (Gigih), Satibi, S. (Syawal)   +2 more
core  

Impact of the height imperfections of masonry blocks on the load bearing capacity of dry-stack masonry walls

, 2018
Dry-stacked masonry walls gives rise to geometric imperfections: the height variation of different masonry blocks ΔH and the roughness of the support area Δh. This paper studies the effect of ΔH on the structural response and the load bearing capacity of
Gelen Gael Chewe Ngapeya, D. Waldmann, F. Scholzen   +2 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Analisis Daya Dukung Tanah Pondasi Dangkal Dengan Beberapa Metode [PDF]

, 2009
This analysis aim to obtain variation of bearing capacity of soil foundation for the same case based on methods is Terzaghi, Meyerhof, Vesic, Hansen and Ohsaki.
Martini, M. (Martini)
core  

Structural effects of steel reinforcement corrosion on statically indeterminate reinforced concrete members [PDF]

, 2016
The final publication is available at Springer via http://dx.doi.org/10.1617/s11527-016-0836-2Steel corrosion in reinforced concrete structures produces loss of reinforcement area and damage in the surrounding concrete.
Bairán García, Jesús Miguel, Fernández Pérez, Ignasi, Herrador Barrios, Manuel F., Marí Bernat, Antonio Ricardo   +3 more
core   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Korelasi Penentuan Daya Dukung Tiang Cara Empirik (Cpt) Dengan Pile Driven Analysis (Pda) Di Kota Pekanbaru [PDF]

, 2007
Axial bearing capacity of pile foundation can be estimated empirically from cone penetration test (CPT). Actual capacity of foundation can be obtained from static load test or pile driving analyzer (PDA).
Nugroho, S. (SA), Yusa, M. (Muhamad)
core