Results 91 to 100 of about 4,772,800 (256)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
MEAN-VARIANCE ANALYSIS OF ALTERNATIVE HEDGING STRATEGIES [PDF]
Demand and Price Analysis,
Hague, Terry +2 more
core +1 more source
The medium isn’t the message: Introducing a measure of adaptive virtual communication
Media use can be considered as an integral part of virtual communication and thus of present-day human interaction. Nevertheless, research on media use and effects still largely relies on laboratory experiments, treating it as a stable input condition ...
Lisa Handke +3 more
doaj +1 more source
Analysis of Molecular Variance (AMOVA) for Autopolyploids
Autopolyploids present several challenges to researchers studying population genetics, since almost all population genetics theory, and the expectations derived from this theory, has been developed for haploids and diploids.
Patrick G. Meirmans, Shenglin Liu
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Statistical Comments on "Assessment of Musculoskeletal Strength and Levels of Fatigue During Different Phases of Menstrual Cycle in Young Adults" [PDF]
Mehrdad Farrokhi, Ali Amani-Beni
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
In order to design of machine or building constructions use of welding connection, there are many factors should beconsidered such as skill, knowledge about welding procedures and material characteristics.
I Dewa Made Krishna Muku
doaj

