Results 101 to 110 of about 168,674,025 (284)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Variance analysis and linear contracts in agencies with distorted performance measures [PDF]

This paper investigates the role of variance analysis procedures in aligning objectives under the condition of distorted performance measurement. A riskneutral agency with linear contracts is analyzed, whereby the agent receives postcontract, pre ...
Budde, Jörg
core  

Statistical Comments on "Assessment of Musculoskeletal Strength and Levels of Fatigue During Different Phases of Menstrual Cycle in Young Adults" [PDF]

Journal of Clinical and Diagnostic Research, 2017
Mehrdad Farrokhi, Ali Amani-Beni
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Variance-covariance loadings for each variable included in the analysis.

, 2020
(A) Variance matrix based on LDA of all measures. (B) Variance matrix based on LDA of ungual bones.
Savannah Elizabeth Cobb (8407758), William I. Sellers (8407761)   +1 more
core   +1 more source

Non-Additivity & Dependency In the Analysis of Variance [PDF]

The Egyptian Statistical Journal, 1975
Ibrahim M. Oweiss
doaj   +1 more source

Application of multivariate analysis of vari-ance (MANOVA) to distance refractive vari-ability and mean distance refractive state

African Vision and Eye Health, 2006
Refractive state can be regarded as a dynam-ic quantity. Multiple measurements of refractive state can be determined easily and rapidly on a number of different occasions using an autore-fractor.
S Abelman
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Model-independent hedging strategies for variance swaps [PDF]

, 2011
A variance swap is a derivative with a path-dependent payoff which allows investors to take positions on the future variability of an asset. In the idealised setting of a continuously monitored variance swap written on an asset with continuous paths, it ...
Klimmek, Martin, Hobson, David, Hobson, D, Klimmek, M   +3 more
core   +1 more source