Results 91 to 100 of about 168,674,025 (284)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The analysis of the NSW wheat variety database. II. Variance component estimation

open access: yes, 1996
The efficiency of various trialling systems for wheat variety evaluation in New South Wales (NSW) is considered. This involved the estimation of the variance components due to genotype, genotype-by-year, genotype-by-location and genotype-by-year-by ...
Thomson, F. M.   +4 more
core   +1 more source

Some aspects of estimators in analysis of variance Model II. [PDF]

open access: yes, 1971
It is well known that the standard estimator for variance components in analysis of variance, Model II, can be a negative with positive probability. In practice, when such an estimator is found to be negative it is taken to be zero.
Green, Gary Allen
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Why do variance swaps exist? [PDF]

open access: yes
This paper studies the determinants of the variance risk premium and concludes on the hedging possibilities offered by variance swaps. We start by showing that the variance risk premium responds to changes in higher order moments of the distribution of ...
Belén Nieto   +2 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Estimation of prediction error variances via Monte Carlo sampling methods using different formulations of the prediction error variance [PDF]

open access: yes, 2009
peer-reviewedCalculation of the exact prediction error variance covariance matrix is often computationally too demanding, which limits its application in REML algorithms, the calculation of accuracies of estimated breeding values and the control of ...
Veerkamp Roel F   +15 more
core   +1 more source

The medium isn’t the message: Introducing a measure of adaptive virtual communication

open access: yesCogent Arts & Humanities, 2018
Media use can be considered as an integral part of virtual communication and thus of present-day human interaction. Nevertheless, research on media use and effects still largely relies on laboratory experiments, treating it as a stable input condition ...
Lisa Handke   +3 more
doaj   +1 more source

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